“清浊祛毒丸”治疗氯胺酮滥用伴泌尿系损害44例疗效观察  

Observation of “Qingzhuoqudu pill”curing 44 patients' urinary system damages induced by ketamine abuse on the clinical symptoms

作　　者：李晓东 秦泽慧[2] 邓菊平 夏子胜 车子瑜 孙海平 梁春梅 何志军 刘权伟 韦品清[2] 

机构地区：[1]珠海金鼎自愿戒毒医院,珠海519085 [2]广州中医药大学,广州510405 [3]惠州罗浮山自愿戒毒医院,惠州516133 [4]万健医疗门诊部,广州510400

出　　处：《中国药物滥用防治杂志》2013年第3期150-155,共6页Chinese Journal of Drug Abuse Prevention and Treatment

摘　　要：目的:通过对"清浊祛毒丸"治疗氯胺酮(K粉)滥用导致泌尿系损害的临床治疗效果观察,探索科学有效的治疗方法。方法:对44例氯胺酮滥用伴有严重泌尿系损害症状患者进行口服"清浊祛毒丸"治疗,通过比较治疗的初日、第七日、第十四日和第二十日(出院前)的临床症状评分,以及相应的实验室尿常规检查结果,观察治疗效果。结果:通过"清浊祛毒丸"的治疗,患者的尿频、尿急、尿痛、血尿等尿路刺激症状明显减轻和消失,尿常规结果逐渐恢复正常,治疗前后结果比较有显著性差异(P<0.05)。结论:"清浊祛毒丸"对缓解和消除氯胺酮滥用导致的泌尿系损害有显著的效果,并且可以减轻和缓解腰痛、乏力、自汗盗汗等戒断症状,具有标本兼治的康复治疗作用,是治疗氯胺酮滥用导致泌尿系损害的有效方法之一。Objective ： In seeking a scientific and effective treatment for ketamine abusers, an observation was conducted on the clinical symptoms of the ketamine abusers who used ＂Qingzhuoqudu pill＂ to cure urinary system damages induced by ketamine abuse. Methods： 44 ketamine abusers who got serious urinary system damage symptoms were given a clinical treatment with oral ＂Qingzhuoqudu pill＂, observation as well as comparison of their lab urine test. The treatment effectiveness was observed by comparing clinical symptom scores of the initial day, the 7th day, the 14＇h and 20＇h day （before discharged ）, as well as the corresponding laboratory urine routine examination results. Results ： The treatment of ＂Qingzhuoqudu pill＂ can obviously ease the symptoms of urinary system tract ir- ritation such as urinary frequency and urgency, dysuria and hematuria. Otherwise the urine routine results gradually returned to normal. Significant differences were found in a comparison before and after treatment（ P 〈 0. 5 ）. Conclusion： ＂Qingzhuoqudu pill＂ has a significant effect to relieve and eliminate urinary system damages induced by ketamine abuse and can relieve backache, fatigue, spontaneous perspiration, night sweats and so on. It can treat both principal and secondary aspect of disease. So ＂Qingzhuoqudu pill＂ would be considered as one of effective medical treatments for ketamine abuse which may lead to urinary tract irritation.

关 键 词：清浊祛毒丸 氯胺酮滥用 泌尿系症状 

分 类 号：R277.7[医药卫生—中医学]