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作 者:林明珠[1] 陈丽梅[1] 温碧霞[1] 谭碧连[1] 陈绮婷[1]
出 处:《国际医药卫生导报》2013年第9期1359-1362,共4页International Medicine and Health Guidance News
摘 要:目的寻求小儿无创正压通气联合雾化更有效舒适的雾化方法。方法选择三种疾病患儿,于同种疾病患儿随机选取相同例数,对照组、观察组按二种雾化方法进行对比。对照组:按传统氧气驱动雾化方法。观察组:按改良氧气驱动雾化方法指安装好的雾化器(同传统方法),但氧表的湿化瓶内放已加温至45℃蒸溜水,喷嘴改直接接无创通气鼻塞喷雾。二组患儿均选择纽邦E360呼吸机辅助通气,喷雾时暂停正压通气,完成雾化再继续接无创正压通气,喷雾20分钟后观察患儿不良反应及排痰效果。结果两组患儿雾化吸入不良反应发生情况比较、雾化吸入排痰效果比较均有统计学意义(P〈0.01)。结论观察组雾化吸入发生不良反应情况明显减少,雾化吸入后排痰效果好,有显著临床意义。Objective To seek a more comfortable and effective inhalation method in noninvasive positive pressure ventilation combined with nasal aerosol inhalation. Methods The pediatric patients with three different diseases were randomly assigned to a control group or a study group based on two kinds of aerosol inhalation method. The control group received traditional oxygen-driven aerosol inhalation; while the study group received modified oxygen-driven aerosol inhalation method (traditional method), with the humidification bottle of the oxygen meter filled with distilled water of 45℃ and a direct connection of nozzle to non-invasive ventilation. The patients in bothgroups were mechanically ventilated via the Pradesh E360. Positive pressure ventilation suspended during aerosol inhalation and then continued after completion of inhalation. The adverse reactions and expectoration effect were observed 20 minutes after aerosol inhalation. Results The rate of adverse reactions and the expectoration effect differed significantly between the two groups (P 〈0.01). Conclusions Aerosol inhalation has fewer adverse reactions and a better expectoration effect, which has marked clinical significance.
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