老年高血压病患者血压变异性与颈动脉内膜中层厚度的相关性  

The correlation between blood pressure variability in patients with hypertension and carotid artery intima-media thickness

作　　者：李珂[1] 雷震武[1] 葛正庆[1] 周传堃[1] 安闽生[1] 李沂[1] 杜荣生[1] 

机构地区：[1]成都大学附属医院心血管内科超声科,四川成都610081

出　　处：《四川医学》2013年第4期470-472,共3页Sichuan Medical Journal

摘　　要：目的以老年高血压病患者为研究对象,探讨颈动脉内膜中层厚度与血压变异性的相关性。方法将102例老年高血压患者分为IMT正常组(n=49)和IMT异常组(n=53),测定患者IMT和血压变异性,之后分析两者之间的相关性。结果老年高血压病患者IMT除与年龄、病程、BMI、TC、TG、HDL-C等指标相关外,24hSBPSD、24hSBPCV、dSB-PSD、dSBPCV、nSBPSD、nSBPCV为IMT的独立危险因素。结论对于老年高血压病患者,在控制血压,干预BMI、TC、TG、HDL-C传统危险因素同时,应重视降低其血压变异性,从而降低靶器官损害和心血管事件。Objective To investigate into the correlation between IMT and BPV in elderly patients with hypertension. Methods 102 cases of elderly hypertension were divided into IMT normal group （ n = 49 ） and IMT abnormal group （ n = 53 ）, measuring IMT and BPV in patients respectively. Then making an analysis of the relationship between them. Results In addition to age, course of disease, BMI, TC, TG, HDL-C, there are other independent risk factors, which include 24hSBPSD, 24hSBPCV, dSBPSD, dSBPCV, nSBPSD, nSBPCV, connected with IMT in elderly hypertensive patients. Conclusion For elderly hypertensive patients, besides controlling the blood pressure and intervening some traditional risk factors like BMI, TC, TG, HDL-C, attention also should be paid to reduce the variability of blood pressure, thereby reducing the target organ damage and cardiovascular events.

关 键 词：老年高血压病 血压变异性 颈动脉内膜中层厚度 

分 类 号：R544.1[医药卫生—心血管疾病]