阿托伐他汀对舒张性心力衰竭患者的BNP和hn-CRP的影响  

Effect of atorvastatin on BNP and hn-CRP in patients with diastolic heart failure

作　　者：唐成玥 唐力[1] 

机构地区：[1]双流县第一人民医院心内科,四川双流610200

出　　处：《四川医学》2013年第4期522-523,共2页Sichuan Medical Journal

摘　　要：目的探讨在常规标准抗心力衰竭药物治疗的基础上加用阿托伐他汀40mg/d对舒张性心力衰竭BNP和hn-CRP的影响。方法将62例舒张性心力衰竭患者随机分为阿托伐他汀组和对照组。对照组给予常规抗心力衰竭药物治疗。阿托伐他汀组在此基础上给予阿托伐他汀40mg/d,分别在治疗前和治疗8周时测定BNP和hn-CRP。结果阿托伐他汀组治疗8周后BNP低于对照组,差异有统计学意义(P<0.05)。结论非缺血性慢性心力衰竭在常规应用抗心力衰竭的基础上加用阿托伐他汀40mg/d是安全有效的,可明显降低BNP和hn-CRP。Objective To investigate the effects of 40mg atorvastatin on BNP and hn-CRP in patients with diastolic heart failure. Methods 62 non-ischemic heart failure patients were equally randomized to receive usual care alone （ control group, n = 31 ） or receive usual care combined 40mg atorvastatin （ atorvastatin group, n = 31 ） , the levels of BNP and hn-CRP before and after treatment were compared. Results Compared with control group, the levels of BNP and hn-CRP in atorvastatin group were decreased significantly. Conclusion Effect of atorvastatin on decreasing the level of BNP and hn-CRP may be beneficial for patients with diastolic heart failure.

关 键 词：阿托伐他汀 舒张性心力衰竭 BNP hn-CRP 

分 类 号：R541.6[医药卫生—心血管疾病]