成都地区过敏性鼻炎患者过敏原的检测分析  

Detection and analysis of allergens in allergic rhinitis patients in Chengdu

作　　者：蒋锐明[1] 范敏[1] 谢亚柳[1] 袁洛花[1] 许琴[2] 

机构地区：[1]成都市第七人民医院耳鼻咽喉科,四川成都610017 [2]成都医学院

出　　处：《四川医学》2013年第4期589-591,共3页Sichuan Medical Journal

摘　　要：目的检测成都地区过敏性鼻炎(AR)患者血清中的过敏原情况,为临床诊断和治疗过敏性鼻炎提供实验室依据。方法过敏性鼻炎患者88例及同期就诊的非过敏性鼻炎患者30例,采用酶免疫斑点法,检测患者血清中的吸入性和食入性过敏原共20项。结果吸入性过敏原前3位为:屋尘螨/粉尘螨组合(65.9%)、屋尘(43.2%)狗上皮(9.1%);食入性过敏原前3位为:虾和海鱼组合(13.6%)、艾蒿(11.4%)、黄豆(10.2%)。30例阴性对照仅有1例检测出阳性过敏原为虾和海鱼。结论屋尘螨/粉尘螨和虾/海鱼分别是导致成都地区AR最主要的吸入性和食入性过敏原,有意识地避免接触这些过敏原及进行特异性的免疫治疗对防治过敏性鼻炎具有积极意义。Objective To detect allergen in serum of patients with allergic rhinitis （AK） Ior cllagnosls and treatment. Methods Sera from 88 AR patients and 30 non-allergic rhinitis controls were collected and detected for 20 kinds of allergen by u- sing enzyme-linked immunospot assay. Results In Chengdu city, the positve rates arrangement of top 3 of inhalant allergens are house dust mite/dermatophagoides farinae （65.9%）, house dust （43.2%） and dog epithelium （9.1%） , respectively and of in- gested allergens are shrimp/marine fish （13.6%） , artemisia argyi （11.4% ） and soybean （10.2%） , respectively. Only I of 30 controls is allergic to shrimp and marine fish. Conclusion House dust mite/derrnatophagoides farinae and shrimp/marine fish are the uppermost inhalant and ingested allergens reepeetively which induced AR in Chengdu city. Dection of allergen is meaningful for patients to prevent suffering from AR disease by avoiding touching these allergens consciously, and it is important for clinicians to perform specific immunotherapy on AR patients.

关 键 词：过敏性鼻炎 过敏原 成都地区 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]