中医证候疗效评价计分表条目筛选分析  

Items Selection Research in Development of Traditional Chinese Medical Syndrome Scale

作　　者：于长禾[1] 王鸿琳[1] 张哲[2] 陈智慧[1] 张会永[2] 杨关林[1] 

机构地区：[1]辽宁中医药大学,辽宁沈阳110032 [2]辽宁中医药大学附属医院,辽宁沈阳110032

出　　处：《中华中医药学刊》2013年第6期1278-1282,共5页Chinese Archives of Traditional Chinese Medicine

基　　金：国家科技部重大新药创制专项课题资助项目(2009ZX09502-29)

摘　　要：目的:经过理论框架构建、条目池建立、核心小组条目初筛等一系列过程形成中医证候疗效评价计分表初稿的基础上,应用主、客观筛选法进一步优化中医证候疗效评价计分表的条目。方法:基于德尔菲专家咨询法,结合Saaty法形成主观法的条目能力排名(Rank1),基于临床调查的频数分布法、离散趋势法、克朗巴赫系数法、因子分析法、相关系数法和重测信度法形成客观法的条目能力排名(Rank8),然后根据主、客观法的条目能力排名形成最终的条目能力综合排名(Rank9)。最后由课题组根据理论框架,以专家意见为主导,参考综合排名进行条目分析对量表进行条目筛选。结果:确定了疾病、证候两个维度,构建中医证候疗效评价计分表条目,初步确定胸痛频率、胸痛持续时间、胸痛程度、胸痛运动耐量,胸闷频率、胸闷持续时间、胸闷程度、胸闷运动耐量,心悸,气短,肢体沉重,口唇紫黯,舌象,脉象14个条目。结论:以专家意见为主导,参考主客观法综合排名的定性定量结合的方法,不仅科学的从条目的重要性、困难度、敏感性、一致性、代表性、相关性(及独立性)和稳定性等7个方面对其进行评价。Objective ： The draft version of Traditional Chinese Medical Syndrome Scale had been developed through the process of the framework establishment, items pooled, and the core group discussion. Based on the draft, we selected and optimized the items by the qualitative and quantitative methods. Method：The Rank 1 was drawn from the combination of the national Delphi and Saaty analysis; and the Rank 8 was concluded from the clinical survey statistics data, such as Frequency Distribution, Dispersion Tendency, Chrobach＇s alpha, Exploratory Factor Analysis, Test - retest Reliability and Correction Coefficients; therefore, the comprehensive ranking Rank 9, combining the quantitative and qualitative methods, could be synthesized by Rank 1 and 8. Finally, the optimized items were selected based on the specialists＇advice and the Rank 9. Results：The first version of Traditional Chinese Medical Syndrome Scale came out with 14 optimized items underlying the disease and syndrome domains. Conclusion：Comprehensive ranking method with the specialists＇ advice could be the best way in selecting and optimizing the items of the scale development.

关 键 词：中医证候 德尔菲 Saaty法 心绞痛 痰瘀互结证 计分表 疗效评价 条目筛选 

分 类 号：R969.4[医药卫生—药理学]