某院近2年革兰阴性杆菌耐药性监测及临床意义  

Antimicrobial resistance of Gram-negative bacilli isolated from a hospital and its clinical significance

作　　者：江镜全[1] 郭旭光[1] 陈琼[1] 夏勇[1] 

机构地区：[1]广州医学院第三附属医院检验科,广东广州510150

出　　处：《检验医学与临床》2013年第11期1350-1351,1353,共3页Laboratory Medicine and Clinic

基　　金：广东省广州市医药卫生科技一般引导项目(项目编号:20121A011160)

摘　　要：目的分析本院2010、2011年临床分离革兰阴性杆菌耐药性,为临床合理用药提供依据。方法采用K-B法进行革兰阴性杆菌药敏试验检测,采用WHONET5.4软件进行数据统计分析。结果 2011年分离革兰阴性菌1 325株,其中大肠埃希菌318株、铜绿假单胞菌266株、鲍曼不动杆菌237株、肺炎克雷伯菌217株,对抗菌药物的敏感率较2010年有所下降。结论革兰阴性杆菌对多种抗菌药物的耐药性明显上升,应加强病原菌耐药性监测,为临床合理用药提供依据。Objective To analyze the drug resistance of Gram-negative bacilli isolated from our hospital in 2010 and 2011 and provide scientific evidence for reasonable usage of antibiotics.Methods Drug sensitivity test was performed by using K-B method and all data were analyzed by using WHONET5.4 software.Results Among 1 325 strains of Gram-negative bacilli,the top four of the isolating rate were Escherichia coli（n=318）,Pseudomonas aeruginosa（n=266）,Acinetobacter baumannii（n=237） and Klebsiellar pneumonia（n=217）,with lower drug sensitivity compared with 2010.Conclusion Drug resistance status of Gram-negative bacilli could be very serious.More attention should be paid to the detection of pathogens and drug resistance in hospital to prevent the outbreak.

关 键 词：革兰阴性杆菌 大肠埃希菌 鲍曼不动杆菌 铜绿假单胞菌 

分 类 号：R378[医药卫生—病原生物学]