镇江市结核病患者耐药情况抽样调查分析  

Sampling survey of drug-resistant tuberculosis in Zhenjiang City

作　　者：戴冰[1] 蒋晖[1] 夏小娟[1] 沈经纬[1] 

机构地区：[1]镇江市疾病预防控制中心慢性传染病防制科,江苏镇江212003

出　　处：《检验医学与临床》2013年第11期1368-1369,共2页Laboratory Medicine and Clinic

摘　　要：目的了解镇江市耐药结核病流行状况,为耐药结核病的预防与控制提供依据。方法按世界卫生组织/国际防痨和肺病联合会《结核病耐药监测指南》的要求进行抽样调查和药敏试验检测,采用SPSS13.0进行数据统计分析。结果镇江市总耐药率达41.7%,其中初始耐药率为31.1%,复治耐药率为58.7%;总耐多药率为19.2%,其中初治耐多药率为9.5%,复治耐多药率为34.8%;女性患者耐多药率高于男性(P<0.05);(>30～50)岁患者耐多药率较高;用药超过1个月的患者耐多药率较高。结论镇江市肺结核患者耐药情况接近全省水平,但不容乐观,需进一步加强耐多药结核病的预防与控制。Objective To understand the status of drug-resistant tuberculosis in Zhenjiang City.Methods The investigation was performed according to World Health Organization/International Union Against Tuberculosis and Lung Disease guidelines,and the results were analyzed by SPSS13.0.Results The total drug resistance rate was 41.7%,the initial drug resistance rate was 31.1% and acquired drug resistance rate was 56.3%.The total multidrug resistance（MDR） rate was 19.2%,the initial MDR rate was 9.5% and the acquired MDR resistance rate was 34.8%.The MDR rate was correlated with gender,age of patient and the duration of medication.Conclusion The overall situation of drug-resistance tuberculosis in Zhenjiang City might be close to the average level of Jiangsu province,but very serious.Further strengthen should paid for the prevention and control of MDR tuberculosis.

关 键 词：结核病 耐药性 分枝杆菌 监测 

分 类 号：R181.3[医药卫生—流行病学]