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机构地区:[1]南京医科大学第一附属医院生殖医学科,210029
出 处:《国际生殖健康/计划生育杂志》2013年第3期198-202,共5页Journal of International Reproductive Health/Family Planning
基 金:国家973项目(2012CB944902;2012CB944703);国家重点临床专科妇科资助
摘 要:青春期多囊卵巢综合征(polycystic ovary syndrome,PCOS)的诊断标准仍存在争议,越来越多的学者赞成使用鹿特丹标准,前提是同时具备3个条件:稀发排卵或不排卵、高雄激素血症、超声下卵巢多囊样改变。对于青春期PCOS患者,如3个条件中只满足2个就做出诊断可能导致诊断过度。代谢综合征和睡眠障碍在青春期PCOS患者中发生率较高,并长期对患者健康造成影响。应采取综合治疗,包括调整生活方式,药物治疗是针对胰岛素抵抗及代谢功能障碍,常使用胰岛素增敏剂。综述青春期PCOS诊断与治疗的进展。The diagnosis criteria of adolescent polycystic ovary syndrome (PCOS) remains controversial. There is growing support for the Rotterdam criteria,to fit all three criteria:oligoovulation or anovulation, hyperandrogenism and polycystic ovaries on pelvic ultrasonography. The adolescent PCOS may be over-diagnosed by the standard 'two of three' criteria. The rates of metabolic syndrome and sleep disorders are higher in those patients with the adolescent PCOS,which likely have implications on long-term health. The lifestyle modification should be included in the comprehensive treatment for the adolescent PCOS, such as diet,exercise and behavioral changes. Medicines are used to treat insulin resistance and metabolic dysfunction, such as insulin sensitizers.
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