免疫性卵巢早衰与T淋巴细胞亚群相关性研究  

Relationship between Autoimmune Premature Ovarian Failure and T Lymphocyte Subsets

作　　者：冯静[1] 李杏杏[1] 王佩娟[2] 

机构地区：[1]南京中医药大学,江苏南京210028 [2]江苏省中西医结合医院,江苏南京210028

出　　处：《吉林中医药》2013年第5期441-443,共3页Jilin Journal of Chinese Medicine

摘　　要：卵巢早衰病因错综复杂,自身免疫因素是卵巢早衰的一个重要原因。T淋巴细胞按其功能可分为辅助性T细胞(helper T cells,Th)、细胞毒T细胞(cytotoxic T cells,Tc)、调节性T细胞(regulatory T cells,Treg)3个亚群。相关研究表明,卵巢早衰与T淋巴细胞亚群关系密切,但卵巢早衰与T淋巴细胞各个亚群之间的关系尚无统一看法,特别是卵巢早衰与辅助性T细胞及细胞毒T细胞的关系尚存在很多争议,而且目前也没有关于卵巢早衰与调节性T细胞的研究报道。因此,探索免疫性卵巢早衰与T淋巴细胞亚群的关系尤为重要。The causes of premature ovarian failure are complex, and autoimmunity is an important reason causing pre- mature ovarian failure. T lymphocytes can be divided into helper T ceils, cytotoxic T cells and regulatory T cells according to their function. Research shows that premature ovarian failure is closely related with T lymphocyte subsets. However, there is no agreement about the relationship between premature ovarian failure and each subset of T lymphocytes. Especially the con- nection between premature ovarian failure and helper T cells and cytotoxic T ceils is controversial, and there is no report about premature ovarian failure and regulatory T ceils. Therefore, it is particularly significant to explore the relationship be- tween autoimmune premature ovarian failure and T lymphocyte subsets.

关 键 词：卵巢早衰 免疫 T淋巴细胞亚群 

分 类 号：R711.75[医药卫生—妇产科学]