影响糖尿病足截肢的相关因素分析  

Analysis of related factors of diabetic foot amputation

作　　者：钟玫[1] 莫建明[1] 颜晓东[1] 黄建皓[1] 农月稠[1] 黄秀碌[1] 谭小燕[1] 

机构地区：[1]广西壮族自治区人民医院内分泌代谢科,南宁530021

出　　处：《齐齐哈尔医学院学报》2013年第10期1405-1407,共3页Journal of Qiqihar Medical University

基　　金：广西卫生厅重点科研课题项目(合同号:桂卫重200811)

摘　　要：目的探讨分析糖尿病足时截肢发生的相关危险因素。方法回顾性分析我院2008年6月至2012年12月住院治疗的436例糖尿病足患者临床资料,分为截肢组和非截肢组,对两组患者的基本资料及生化指标进行分析。结果我院436例糖尿病足患者住院期间截肢发生率为20.41%(89/436)。吸烟、白细胞计数、血红蛋白、总胆固醇、甘油三酯、HDL-C、LDL-C、血浆白蛋白、S-CRP、ABI≥0.3、超声示闭塞是被筛出来的有意义变量,多因素逐步logistic回归分析得出血白细胞计数(β=1.188,OR=1.843)、总胆固醇(β=1.175,OR=2.230)、血红蛋白(β=1.520,OR=3.634)、HDL-C(β=1.067,OR=1.810)、糖化血红蛋白(β=1.114,OR=3.236)、下肢血管病变(β=1.184,OR=1.237)、S-CRP(β=1.404,OR=1.232)是截肢的独立危险因素(P<0.05)。结论针对糖尿病足危险因素的患者需要加强控制血糖,加强抗感染、改善血管循环、改善全身营养状况,预防截肢的发生。Objective To investigate the risk factors of diabetic foot amputation. Methods Retrospective analysis of our hospital from 2008 June to 2012 December were the clinical data of 436 patients with diabetic foot treatment, divided into amputation group and non amputation group, carries on the analysis to the basic data of the two groups of patients and biochemical indexes. Results In our hospital, 436 cases of diabetic foot patients hospitalized during the amputation rate was 20.41% （89/436）. Multivariate logistic regression analysis the blood white cell count （ β = 1. 188, OR = 1. 843 ）, total cholesterol （ 13 = 1. 175, OR = 2. 230 ）, hemoglobin （ 13 = 1. 520, OR = 3. 634 ）, HDL-C （ β = 1. 067, OR = 1. 810）, Glycosylated hemoglobin （ 13 = 1.114, OR = 3. 236 ）, peripheral vascular disease （ 13 = 1. 184, OR = 1. 237 ） , S-CRP （ 13 = 1. 404, OR = 1. 232 ） was an independent risk factor for amputation （ P 〈 0.05 ）. Conclusions For patients with risk factors of diabetic foot, we need to strengthen the control of blood glucose, anti infection, improve blood circulation, improve the nutritional status of the body, and prevent the occurrence of amputation.

关 键 词：糖尿病 糖尿病足 危险因素分析 截肢 

分 类 号：R587.2[医药卫生—内分泌]