2009-2011年门诊处方抗菌药物的应用情况  

Use of antibacterial prescriptions in outpatient in 2009-2011

作　　者：王向荣[1] 李忠东[2] 王川[2] 李耀武[1] 

机构地区：[1]空军总医院计划科,北京100142 [2]空军总医院药学部,北京100142

出　　处：《临床药物治疗杂志》2013年第3期54-58,62,共6页Clinical Medication Journal

摘　　要：目的:分析我院门诊处方中抗菌药物的应用情况,为加强合理用药管理提供参考。方法:每月盲法抽取我院2009-2011年度门诊患者处方2000张,通过金额排序法、用药频度排序法和药物利用指数回顾性分析抗菌药物的合理应用情况。结果:2009-2011年我院门诊抗菌药物处方占所有处方的比例均小于20%且逐年下降,抗菌药物金额也逐年减少。金额构成比排序前5位的抗菌药物种类有第3代头孢菌素、青霉类、喹诺酮类、大环内酯类;金额构成比排序前5位的药物有头孢地尼、头孢唑肟、莫西沙星、依替米星、阿奇霉素,其中头孢地尼金额构成比在3年均排在第1位。2009年DDDs值排在第1位的是阿奇霉素口服制剂,2010年是头孢呋辛酯口服制剂,2011年是阿莫西林口服制剂。2009年DUI≤1的不同剂型的抗菌药物占79.6%,2010年的占84.8%,2011年的占67.3%。结论:该院门诊抗菌药物应用的合理性需进一步提高,应从制定使用权限、规范医生使用抗菌药行为等加强使用管理。Objective： To analyze use of antibacterial prescriptions in outpatient of general hospital of air force from 2009 through 2011 in order to provide some references for guiding and managing clinical use of antibacterials. Methods： Antibacterial use was analyzed by consumption sum, defined daily dose（DDD）,DDDs and drug utilization index （ DUI ）. Results： Antibacterial prescription accounted for less than 20% of all the prescriptions and decreased from 2009 through 2011. The consumption sum of anti-bacterial agents also decreased gradually, the top 5 constituent ratio of consumption sum of antibacterials class were the third- generation cephalosporins, penicillins, quinolones and macrolides, respectively, the top 5 constituent ratio of consumption sum of drugs were cefdinir, ceftizoxime, moxifloxacin, etimicin and azithromycin. The ranking of consumption sum of cefdinir was in top one for 3 years. The azithromycin oral preparations was top one value of DDDs in 2009, and cefuroxime axetil oral preparations in 2010, and amoxicillin oral preparations in 2011. The constituent ratios of anti-bacterial agents in different preparations whose DUI were less than 1 in 2009 ,in 2010 and in 2011 were 79.6%, 84.8% and 67.3%, respectively. Conclusion： The rationality of use of antibacterial agents in the outpatient of our hospital should be further improved, and the management of doctors＇ authority of antibacterial agents use and their behavior of standardizing use of antibacterial drug and so on should be strengthened.

关 键 词：抗菌药物 合理用药 用药频度 

分 类 号：R969.3[医药卫生—药理学]