得普利麻注射液的并发症研究及防范  

Investigation and Prevention of Complications Induced by Propofol Injection

作　　者：肖生红[1] 刘先保[1] 詹鸿[1] 

机构地区：[1]广州医学院第三附属医院,510150

出　　处：《岭南急诊医学杂志》2013年第2期119-120,共2页Lingnan Journal of Emergency Medicine

摘　　要：目的:探讨得普利麻注射液的麻醉风险及严重并发症的预防,以提高其使用的安全性。方法:回顾性分析2002年1月至2012年12月应用得普利麻注射液麻醉98307例患者的各种并发症及危险性。结果:98307例单纯使用得普利麻注射液的患者99.99%有注射痛感;99.99%的患者血压下降30%,92.12%的患者SpO_2下降到90%,0.02%的患者拉起下额角后SpO_2仍小于60%并有返流、误吸,必须放口咽通气道,心跳骤停2例,经抢救成活1例,死亡1例。结论:得普利麻注射液导致的最大风险及最严重的并发症是返流误吸致上呼吸道梗阻、窒息、缺氧,抢救不及时可致死,使用该药需备好口咽通气道。Objective：To explore the anesthesia risks and to prevent the severe complications of Propofol Injection so as to improve the safety of the medicine. Methods： The anesthesia risks and severe complications of 98307 cases were given Propofol Injection were analyzed retrospectively from Jan 2002 to Dec 2012. Results：Among the 98307 cases were given Propofol Injection, 99.99% of the cases had pain during injection, 99.99% had the decrease of blood pressure 30% as much as the previous pressure,92.12% had the decrease of SpO2 to 90% ,0.02% had the rise of inferior frontal angle ,60% had back flow aspiration and needed oropharynx parichnos, 2 cases had cardiac arrest, one case was alive and another was dead. Conclusions： Back flow aspiration is the severest complication of Propofol Injection, which can result into upper respiratory tract obstruction and will cause death if failing in prompt rescue. It must prepare an oropharynx parichnos before using Propofol Injection.

关 键 词：得普利麻注射液 风险 并发症 预防 

分 类 号：R614[医药卫生—麻醉学]