微泵注入与肌注氯解磷定对急性有机磷中毒的疗效比较  

The Effect Compare of Patients with Acute Organophosphate Poisoning Treated by Pralidoxime Chloride Using Intramuscularly and Micro-pump

作　　者：陈翠珍[1] 罗秋平[1] 张燕琴[1] 唐海艳[1] 

机构地区：[1]广东省湛江中心人民医院,524037

出　　处：《岭南急诊医学杂志》2013年第2期131-132,共2页Lingnan Journal of Emergency Medicine

摘　　要：目的:比较氯解磷定微泵与肌注二种不同的给药方式在救治急性有机磷中毒中的治疗效果。方法:将42例急性有机磷农药中毒患者在常规对抗毒蕈碱样症状治疗基础上按就诊顺序单号和双号分为观察组和对照组各21例,观察组采用微泵注入氯解磷定的方式,对照组应用肌注氯解磷定的方式,比较两组患者的治疗效果和胆碱酯酶(ChE)的恢复情况。结果:观察组中胆碱酯酶的恢复时间、氯解磷定的总量、从昏迷到清醒时间和住院的平均时间均明显小于对照组(P<0.05)。结论:微泵注入氯解磷定治疗急性有机磷中毒的效果明显优于肌注氯解磷定。Objective： To compare the clinical effect of patient with acute organophosphate treated poisoning by pralidoxime chloride using intramuscularly and micro-pump. Method： 42 patients with acute organophosphate poisoning in conventional treatment against muscarinic symptoms based on the sequence by a single number and two-doctor Number were divided into observation group and control group, and each group was 21 cases. The observation group was accepted pralidoxime chloride by micro-pump, while the control group was accepted pralidoxime chloride by intramuscular. The clinical effect and the recovery of eholinesterase were compared between the two groups. Results： The recovery time and the amount of pralidoxime chloride, from coma to awake and the average hospitalization time in the observation group were significantly less than those in the control group （P 〈 0.05）. Conclusion：The clinical effect of patients with organophosphorus poisoning treated by pralidoxime chloride using micro-pump is better than using intramuscular.

关 键 词：微泵注入 肌注 急性有机磷中毒 临床疗效 

分 类 号：R595.4[医药卫生—内科学]