腹膜透析治疗尿毒症难治性高血压的临床研究  

作　　者：钟汉[1] 伍锦泉[2] 陈玉平[2] 

机构地区：[1]肇庆市第三人民医院肾内科,广东526000 [2]肇庆市第一人民医院肾内科,广东526000

出　　处：《当代医学》2013年第16期91-92,共2页Contemporary Medicine

摘　　要：目的探讨腹膜透析和血液透析方法对尿毒症并发难治性高血压患者的临床疗效。方法 60例尿毒症难治性高血压患者随机分为血液透析(HD组)和腹膜透析(CAPD组),透析3个月。HD组透析时间每次3.5～4.5h,每周2～3次。CAPD组每次入液量2000mL,保留腹中3～4h。观察治疗前后尿素氮(Bun)、肌酐以及高血压控制疗效。结果两组患者治疗后,血清Bun及Cr均降低,HD组透析前后Bun及Cr差值均高于CAPD组,但两者比较无显著性差异,P>0.05。HD组透析治疗后,收缩压和舒张压降低均不显著,差异无统计学意义,P>0.05;而CAPD组患者透析后血压均显著下降,透析前后比较有显著性差异,P<0.01。结论 HD和CAPD均为终末期肾病的有效治疗方法,在合并顽固性高血压患者中,CAPD对于控制血压方面与HD比较仍具有一定的优势。Objective To compare the clinic therapeutic effect of hemodialysis and continuous ambulatory peritoneal dialysis effect and the effect on blood pressure in uremic patients with refractory hypertension. Methods Sixty uremic patients with refractory hypertension were randomLy divided into two groups, HD and CAPD group. Dialysis continued 3.5-4.5 h in HD group 2-3 times every week. The volume dose of peritoneal dialysis fluid for CAPD group was 2000 mL, which contained in abdomen for 3-4 h. After dialyzed for 3 months, then Bun, Cr and the effect on blood pressure were observed and compared. Results After treatment, the levels of Bun, Cr fell significantly in both groups. And equation value of the Bun, Cr between pre^dialysis and post-dialysis in HD group were higher than in CAPD group, but no statistical significance were observed, P〉0.05. After dialysis in HD group, contractive pressure and diastolic pressure fell lowly, there was no statistical significance, P〉0.05; but contractive pressure and diastolic pressure fell significantly in CAPD group, there was statistical significance,P〈0.01. Conclusion HD and CAPD were the treatment methods in uremic patients. But CAPD was predominance to HD in the treatment effect on blood pressure in uremic patients with refractory hypertension.

关 键 词：腹膜透析 血液透析滤过 高血压 终末期肾衰竭 

分 类 号：R692.5[医药卫生—泌尿科学]