气相色谱-质谱法检测中药材中81种农药残留  

Determination of 81 Pesticide Residues in Chinese Herbal Medicines by Gas Chromatography-Mass Spectrometry

作　　者：何芳[1] 孔祥虹[1,2] 何强 高军刚[1] 

机构地区：[1]陕西师范大学,西安710061 [2]陕西出入境检验检疫局,西安710068

出　　处：《化学分析计量》2013年第3期9-13,共5页Chemical Analysis And Meterage

基　　金：国家质检公益性科研项目(201010040);国家质检总局科研项目(2009IK285)

摘　　要：建立气相色谱-质谱(GC-MS)法测定中药材中81种农药残留的分析方法。样品用含0.1%乙酸的乙腈提取后用GPC或GPC-SPE固相萃取净化,在选择离子监测模式(SIM)下对天麻、杜仲、金银花、山茱萸进行测定。方法在0.01～1.0μg/mL范围内具有良好的线性关系,相关系数均大于0.999,检出限为6.0～31.9μg/kg,加标回收率为60.8%～128.9%,测定结果的相对标准偏差为7.6%～18.9%(n=6)。该方法操作简便,灵敏度、准确度和精密度均符合农药多残留检测技术要求,适用于中药材中81种农药多残留的测定。The determination of 81 pesticide residues in Chinese herbal medicines by gas chromatography-mass spectrometry（GC-MS） was developed. Samples were extracted with 0.1% acetic acid-acetonitrile solution, then cleaned up with GPC or GPC-SPE, and determined by GC-MS with selective ion monitoring（SIM） mode. The result showed that a good linear relationship was obtained in the range of 0.01-1.0 μg/mL. The correlation coefficients were larger than 0.999. The detection limits were 6.0-31.9 μg/kg, the recoveries were 60.8%-128.6% and the relative standard deviations of determination results were 7.6%-18.9%（n=6）. The proposed method is highly sensitive, accurate and reliable to meet the requirements of the multiple pesticide residues analysis in Chinese herbal medicines.

关 键 词：气相色谱-质谱法 中药材 农药残留 

分 类 号：O657.7[理学—分析化学]