松针叶绿素-胡萝卜素软膏对幽门螺杆菌的体外抑菌作用  

Antibacterial activity in vitro of chlorophyll-carotene paste from pine needles on Helicobacter pylori

作　　者：郑光耀[1,2,3] 薄采颖[1,2,3] 何玲[4] 李骄[5] 李海涛[5] 

机构地区：[1]中国林业科学研究院林产化学工业研究所 [2]国家林业局林产化学工程重点开放性实验室 [3]生物质化学利用国家工程实验室,江苏南京210042 [4]中国药科大学药理学教研室,江苏南京210009 [5]南京中医药大学药学院,江苏南京210046

出　　处：《时珍国医国药》2013年第5期1079-1080,共2页Lishizhen Medicine and Materia Medica Research

基　　金：科技部农业科技成果转化资金项目(No.2008GB24320412);教育部“新世纪优秀人才”支持计划资助项目(No.NCET-10-0817);国家“十二五”重大新药创制专项(No.2012ZX09504001-001)

摘　　要：目的考察松针叶绿素-胡萝卜素软膏对幽门螺杆菌的体外抑菌作用。方法采用试管两倍稀释法测定松针叶绿素-胡萝卜素软膏的最低抑菌浓度(MIC)和最低杀菌浓度(MBC)。结果松针叶绿素-胡萝卜素软膏对幽门螺杆菌的MIC为1∶32,MBC为1∶8。结论松针叶绿素-胡萝卜素软膏在体外具有较强的抑制幽门螺杆菌作用。Objective To investigate the antibacterial activity in vitro of chlorophyll-carotene paste from pine needles on Helicobacter pylori（Hp）. MethodsThe method of doubling dilution in tubes was used in susceptibility test,the minimal inhibitory concentration（MIC） and minimum bactericidal concentration（MBC） were determined. ResultsThe chlorophyll-carotene paste from pine needles have antibacterial activity on Hp which MIC was 1∶32 and MBC was 1∶8. ConclusionThe chlorophyll-carotene paste from pine needles have antibacterial activity on Hp in vitro.

关 键 词：松针 提取物 幽门螺杆菌 抑菌作用 

分 类 号：R285.5[医药卫生—中药学]