基于药浴治疗慢性肾脏病安全性相关机制研究探讨壮火食气的内涵  

The Discussion of the Mechanism of "Evil Fire Exhaust Qi" by Observation of the Nephritis of 30 Collapse CKD Patients in the Process of Medicated Bath

作　　者：马俊杰[1] 周春祥[1] 

机构地区：[1]南京中医药大学基础医学院,江苏南京210046

出　　处：《时珍国医国药》2013年第5期1272-1273,共2页Lishizhen Medicine and Materia Medica Research

基　　金：国家科技部"十一五"支撑项目(No.2008BAI53B068)

摘　　要：目的观察药浴疗法治疗慢性肾脏病过程中休克患者的发生机制,并做出相应安全性评价。方法 30例药浴治疗过程中发生休克的慢性肾脏病患者,在休克前后分别测定GFR、血肌酐、D-二聚体、肾素-血管紧张素II-醛固酮、hs-C反应蛋白、TNF-α、IL-6。结果患者发生休克前后的GFR、血肌酐、D-二聚体、肾素-血管紧张素II-醛固酮、hs-C反应蛋白、TNF-α、IL-6水平有显著的差异(P<0.05),具有统计学意义。结论药浴治疗慢性肾脏病发生休克导致肾功能恶化与凝血系统、RAS系统及免疫系统有关。Objective discuss the mechanism of Collapse CKD patients in the process of Medicated bath,and giving the Evaluation of Safety. MethodsTo determinate GFR、 serum creatinine、D-dimer 、RAS、hs-C-reactive protein、TNF-α、IL-6before and after collapsion. ResultsGFR、Serum creatinine、D-dimer、RAS、 hs-C-reactive protein、TNF-α、IL-6 were statistically significant differences before and after collapsion. ConclusionDeterioration of renal function by the collapsion in the process of Medicated bath was related to the coagulation system、RAS system and immune system.

关 键 词：药浴 慢性肾脏病 休克 安全性评价 壮火食气 

分 类 号：R2-03[医药卫生—中医学]