An efficient chlorination of aromatic compounds using a catalytic amount of iodobenzene  

作　　者：Ting-Ting Li Cui Xu Chang-Bin Xiang Jie Yan 

机构地区：[1]College of Chemical Engineering and Materials Sciences,Zhejiang University of Technology [2]Foreign Language School,Zhejiang Shuren University

出　　处：《Chinese Chemical Letters》2013年第6期535-538,共4页中国化学快报（英文版）

基　　金：Financial support from the Natural Science Foundation of China (No.21072176)

摘　　要：An efficient method was developed for chlorination of aromatic compounds with electron-donating groups using iodobenzene as the catalyst and m-chloroperbenzoic acid as the terminal oxidant in the presence of 4-methylbenzenesulfonic acid in THF at room temperature for 24 h,and a series of the monochlorinated compounds was obtained in good yields.In this protocol,the catalyst iodobenzene was first oxidized into the hypervalent iodine intermediate,which then treated with lithium chloride and finally reacted with aromatic compounds to form the chlorinated compounds.An efficient method was developed for chlorination of aromatic compounds with electron-donating groups using iodobenzene as the catalyst and m-chloroperbenzoic acid as the terminal oxidant in the presence of 4-methylbenzenesulfonic acid in THF at room temperature for 24 h,and a series of the monochlorinated compounds was obtained in good yields.In this protocol,the catalyst iodobenzene was first oxidized into the hypervalent iodine intermediate,which then treated with lithium chloride and finally reacted with aromatic compounds to form the chlorinated compounds.

关 键 词：Hypervalent iodine intermediate Chlorination Catalytic oxidation Synthesis 

分 类 号：O621.25[理学—有机化学]