2009～2011年急诊科病原菌的分布及耐药性分析  

Distribution and drug resistance analysis of pathogens in emergency department from 2009 to 2011

作　　者：凌文辉[1] 黄汉[2] 廖康[2] 

机构地区：[1]珠海市人民医院检验科,广东珠海519000 [2]中山大学附属第一医院检验医学部,广东广州510080

出　　处：《国际检验医学杂志》2013年第10期1251-1252,共2页International Journal of Laboratory Medicine

摘　　要：目的了解该院急诊科的病原菌分布和耐药性。方法回顾性分析中山大学附属第一医院急诊科2009～2011年病原菌的菌群分布和药敏结果。结果共167株病原菌,其中革兰阴性杆菌111株,占66.5%;革兰阳性菌52株,占31.1%,其他细菌4株,占2.4%。前五位病原菌依次为大肠埃希菌(28.7%)、铜绿假单胞菌(11.7%)、金黄色葡萄球菌(9.9%)、凝固酶阴性葡萄球菌(9.9%)、鲍曼不动杆菌(9.4%)。大肠埃希菌、肺炎克雷伯菌超广谱β内酰胺酶(ESBLs)的检出率分别是70.0%和36.4%,鲍曼不动杆菌对多种抗菌药物的耐药率高;未发现对万古霉素和利奈唑胺耐药的金黄色葡萄球菌、凝固酶阴性葡萄球菌,耐苯唑西林金黄色葡萄球菌(MRSA)和耐苯唑西林凝固酶阴性葡萄球菌(MRSCON)的检出率分别是58.8%和82.4%。结论急诊科的病原菌以大肠埃希菌、铜绿假单胞菌、金黄色葡萄球菌多见,且以血行感染为主。病原菌的对常见抗菌药物的耐药率各有不同,应及时监测病原菌耐药性的变化,合理使用抗菌药物,减少耐药菌株的产生。Objective To investigate the distribution and drug resistance of pathogens isolated from emergency department in The First Affiliated Hospital of Sun Yat-Sen University.Methods Retrospective analysis the distribution and antimicrobial susceptibility test results of pathogens isolated from emergency department in The First Affiliated Hospital of Sun Yat-Sen University.Results Of total of 167 bacterial strains,Gram negative organisms accounted for 66.5% and Gram positive cocci for 31.1%,other bacterium for 2.4%.The top five isolates were E.coli（28.7%）,P.aeruginosa（11.7%）,S.aureus（9.9%）,S.Coagulase-negative（9.9%）and A.baumannii（9.4%）.The detection rates of E.coli and K.pneumoniae producing Extended Spectyum β Lactamases ware 70% and 36.4%.The drug resistance rates of A.baumannii to many antibiotics were high.Vancomaycin or Linezolid resistance of S.aureus and S.coagulase negative were undectected.The detection rates of Methicillin-Resistant S.aureus（MRSA） and Methicillin-resistant S.coagulase-negative（MRSCON） were 58.8% and 82.4%.Conclusion E.coli,P.aeruginosa and S.aureus were main pathogens isolated from emergence department,and bloodstream infection is commonly.The resistance rate of pathogens to usual antibiotics is different.To reduce resistant strains,we should monitor the change of drug resistance of pathogens in time and use antibiotics rationally.

关 键 词：急诊室 医院 病原菌 药物耐受性 

分 类 号：R446.5[医药卫生—诊断学]