青海省2008-2012年急性驰缓性麻痹病例与健康人群病原学监测  

Etiology surveillance on acute flaccid paralysis cases and healthy crowds in Qinghai from 2008 to 2012

作　　者：范丽霞[1] 巴卓玛[1] 赵生仓 

机构地区：[1]青海省疾病预防控制中心,西宁810007

出　　处：《医学动物防制》2013年第5期490-492,共3页Journal of Medical Pest Control

基　　金：国家科技重大专项传染病监测技术平台项目(2009ZX10004-208)

摘　　要：目的分析急性驰缓性麻痹(acute flaccid paralysis,AFP)病例、健康人群粪便标本病原学监测结果,为保持无脊灰状态提供实验室依据。方法病毒分离及鉴定,脊灰病毒株型内鉴别,确定疫苗株或野病毒株。结果青海省2008-2012年AFP病例、健康人群粪便标本782份,分离出脊髓灰质炎病毒2株,分离率为0.26%,其中脊灰I型疫苗株1株,脊灰混合型疫苗株1株,无脊灰野病毒株。分离到非脊灰肠道病毒(non-polio enterovirus,NPEV)162株,分离率为20.72%。结论我省2008-2012年无本地脊灰野毒株病例流行,阻断了脊灰本地野病毒的传播,保持了无脊灰状态。Objective To analyze the etiology surveillance on acute flaccid paralysis（AFP） cases and stool specimens of healthy crowds,so as to provide the laboratory basis for maintaining polio-free status.Method Virus isolation and identification was used,and the strains were determined by the identification within type of poliovirus.Results It was shown that 782 stool specimens of AFP cases and healthy crowds were detected from 2008 to 2012 in Qinghai Province,and 2 strains of poliovirus were isolated,the isolation rate was 0.26%,including 1 strains of poliovirus type I vaccine strain,1 strains of hybrid poliovirus vaccine strain,and no wild poliovirus strain.Furthermore,162 strains of non-polio enteroviruses（NPEV） were isolated,and the isolation rate was 20.72%.Conclusions There was no prevalence of local wild poliovirus from 2008 to 2012 in Qinghai Province,which illustrated that we block the spread of local wild poliovirus effectively,and maintain polio-free status.

关 键 词：脊髓灰质炎病毒 非脊灰肠道病毒 病原学监测 

分 类 号：R181.8[医药卫生—流行病学] R512.4[医药卫生—公共卫生与预防医学]