Cumulative Live Birth Rate after Three Ovarian Stimulation IVF Cycles for Poor Ovarian Responders According to the Bologna Criteria  

作　　者：柯慧 陈薪 刘玉东 叶德盛 何于夏 陈士岭 

机构地区：[1]Centre for Reproductive Medicine,Department of Gynecology and Obstetrics,Nanfang Hospital,Southern Medical University

出　　处：《Journal of Huazhong University of Science and Technology(Medical Sciences)》2013年第3期418-422,共5页华中科技大学学报（医学英德文版）

基　　金：supported by grants from Comprehensive Strategic Sciences Cooperation Projects of Guangdong Province and Chinese Academy (No. 2010B090301026);Guangzhou Science and Technology Program Key Projects (No. 11C22120737);National Natural Science Foundation of China (No. 81170574);Scientific Research Plan of Southern Medical University

摘　　要：Summary： This study explored the cumulative live birth rate after three ovarian stimulation in vitro fer- tilization （IVF） cycles for poor ovarian responders according to the Bologna criteria. In this retrospec- tive cohort study, 479 poor ovarian responders according to the Bologna criteria in the first ovarian stimulation IVF cycle between July 2006 and January 2012 in our IVF centre were included. The cu- mulative live birth rate was calculated by optimistic and pessimistic methods. The cumulative live birth rate after three ovarian stimulation IVF cycles for poor ovarian responders according to the Bologna criteria was 12.7%-20.5%. The three-cycle cumulative live birth rate was 18.5%--24.5%, 13.2%-27.4% and 8.6%-14.9% for poor responders aged ≤35 years, 36-39 years and 〉40 years, re- spectively. In conclusion, poor responders according to the Bologna criteria can receive an acceptable cumulative live birth, rate after three ovarian stimulation IVF cycles, especially poor responders aged 〈40 years.Summary： This study explored the cumulative live birth rate after three ovarian stimulation in vitro fer- tilization （IVF） cycles for poor ovarian responders according to the Bologna criteria. In this retrospec- tive cohort study, 479 poor ovarian responders according to the Bologna criteria in the first ovarian stimulation IVF cycle between July 2006 and January 2012 in our IVF centre were included. The cu- mulative live birth rate was calculated by optimistic and pessimistic methods. The cumulative live birth rate after three ovarian stimulation IVF cycles for poor ovarian responders according to the Bologna criteria was 12.7%-20.5%. The three-cycle cumulative live birth rate was 18.5%--24.5%, 13.2%-27.4% and 8.6%-14.9% for poor responders aged ≤35 years, 36-39 years and 〉40 years, re- spectively. In conclusion, poor responders according to the Bologna criteria can receive an acceptable cumulative live birth, rate after three ovarian stimulation IVF cycles, especially poor responders aged 〈40 years.

关 键 词：ovarian stimulation in vitro fertilization Bologna criteria poor responders cumulative live birth 

分 类 号：R714.8[医药卫生—妇产科学]