针刺对短暂性脑缺血发作患者GMP-140、TXB_2、PGI_2的影响  

Effect of Acupuncture on GMP-140, TXB_2, and PGI_2 in Patients with Transient Ischemic Attack

作　　者：欧阳泠星 潘朝霞 王剑峰 熊同学 汪胤 曾莹莹 向冬枚 曾红梅 陈焕新 黄壑霏 

机构地区：[1]广东省清远市中医院,清远511500

出　　处：《上海针灸杂志》2013年第6期451-453,共3页Shanghai Journal of Acupuncture and Moxibustion

基　　金：广东省中医药管理局课题(20112065)

摘　　要：目的观察针刺对短暂性脑缺血发作(TIA)的GMP-140、TXB2、PGI2的影响及临床疗效。方法将60例TIA患者随机分为针刺组和药物组(阿司匹林)。于治疗前后检测患者GMP-140、TXB2、PGI2并比较疗效。结果治疗前两组血浆GMP-140、TXB2、PGI2含量比较差异无统计学意义(P>0.05);治疗后两组血浆PGI2均有升高(P<0.05),GMP-140、TXB2均有下降(P<0.05,P<0.01);两组治疗后血浆PGI2、GMP-140和TXB2含量比较差异均有统计学意义(P<0.05)。针刺组总有效率为96.7%,药物组为73.3%,两组比较差异有统计学意义(P<0.05)。结论针刺和阿司匹林对TIA的GMP-140、TXB2、PGI2都有较大的影响,但针刺组的变化及临床疗效较药物组显著。Objective To observe the effect of acupuncture on GMP-140, TXB2, and PGI2 in Transient Ischemic Attack （TIA） and its therapeutic effect. Method Sixty TIA patients were randomized into an acupuncture group and a medication group （Aspirin） GMP-140, TXB2, and PGI2 contents were determined before and after treatment, and therapeutic effects were compared. Result Before treatment, there were no significant differences between the two groups in comparing plasma GMP-140, TXB2, and PGI2 contents （P〉0.05）; after treatment, PGI2 increased markedly （P〈0.05） and GMP-140 and TXB2 decreased markedly （P〈0.05,P〈 0.01） in both groups; after treatment, there were significant differences between the two groups in comparing plasma GMP-140, TXB2, and PGI2 contents （P〈0.05）. The total effective rate was 96.7% in the acupuncture group versus 73.3% in the medication group, and the difference was statistically significant （P〈0.05）. Conclusion Acupuncture and Aspirin both have significant effects on GMP-140, TXB2, and PGI2 contents in TIA, but the changes in the acupuncture group and its therapeutic effect are more significant than those in the medication group.

关 键 词：脑缺血 暂时性 GMP-140 血栓烷B2 依前列醇 针刺 刺血疗法 

分 类 号：R246.6[医药卫生—针灸推拿学]