注射用比阿培南质量研究进展  

Advance in the quality research of biapenem for injection

作　　者：贾燕花[1] 邢维伟[2] 

机构地区：[1]解放军总医院第一附属医院药剂药理科,北京100048 [2]国家知识产权局专利局,北京100088

出　　处：《中国新药杂志》2013年第11期1285-1288,共4页Chinese Journal of New Drugs

摘　　要：比阿培南为碳青酶烯类抗生素,属于广谱抗菌药。为了便于比阿培南的质量控制研究,本文综述了近年来国内外文献中关于比阿培南含量、有关物质、聚合物以及残留溶剂等,总结了比阿培南有关物质限度规定,为比阿培南有关物质的研究提供参考与借鉴。Biapenem is a new parenteral carbapenem antibacterial agent with a broad spectrum of antibacterial activity. Here we reviewed determination methods of its content, related substances, polymer and residual solvents in biapenem, and its pharmaceutical preparations in recent years. Furthermore, the limits of impurities in biapenem and its pharmaceutical preparations were summarized. These will provide a reference for the research of related substances in biapenem.

关 键 词：比阿培南 质量研究 注射 

分 类 号：R978.5[医药卫生—药品]