Gold nanoparticles based digital color analysis for quinidine detection  

作　　者：ZOU BoZhou LIU Yue YAN XiaoLi HUANG ChengZhi 

机构地区：[1]College of Chemistry and Chemical Engineering,Education Ministry Key Laboratory on Luminescence and Real-Time Analysis,Southwest University [2]College of Pharmaceutical Sciences,Southwest University

出　　处：《Chinese Science Bulletin》2013年第18期2027-2032,共6页

基　　金：supported by the National Natural Science Foundation of China (21035005);the National Special Major Project of Science and Technology for Creation of New Drugs (20102X09401-306-1-4)

摘　　要：In this contribution,we developed a novel digital color analysis of gold nanoparticles(AuNPs) for pharmaceutical detection by choosing quinidine as an example.It was found that the color of AuNPs colloid solution changed from red to blue in the presence of different concentrations of quinidine,and the color information of each solution could be digitalized with tricolor(RGB) system.Under the optimum conditions,the R value of the solution was found to be linear with the natural logarithm of concentration of quinidine in the range of 112 384 nmol/L.This method has the advantages of rapid,economical and simple,and can serve as a potential alternative to traditional spectrophotometry for practical use.In this contribution, we developed a novel digital color analysis of gold nanoparticles （AuNPs） for pharmaceutical detection by choosing quinidine as an example. It was found that the color of AuNPs colloid solution changed from red to blue in the presence of different concentrations of quinidine, and the color information of each solution could be digitalized with tricolor （RGB） sys- tem. Under the optimum conditions, the R value of the solution was found to be linear with the natural logarithm of concentration of quinidine in the range of 112-384 nmol/L. This method has the advantages of rapid, economical and simple, and can serve as a potential alternative to traditional spectrophotometry for practical use.

关 键 词：金纳米粒子 数字彩色 检测分析 基础 胶体溶液 颜色信息 药品检测 最佳条件 

分 类 号：O657.3[理学—分析化学]