徐州市区糖尿病及糖调节受损患病现况调查及危险因素分析  

Analyzing the morbidities and risk factors of diabetes mellitus and impaired glucose regulation among urban residents in Xuzhou

作　　者：张庆华[1] 凌宏威[2] 应长江[2] 赵猛[2] 王慧[1] 吕霄[1] 李伟[2] 

机构地区：[1]徐州医学院研究生学院,江苏省徐州221000 [2]徐州医学院附属医院内分泌科

出　　处：《中国慢性病预防与控制》2013年第3期277-281,共5页Chinese Journal of Prevention and Control of Chronic Diseases

基　　金：江苏省自然科学基金资助项目(BK2010181);徐州市科技项目(XM09B067)

摘　　要：目的了解徐州市区居民的糖尿病(DM)及糖调节受损(IGR)患病情况,分析相关的危险因素,为制定进一步的防治策略及工作提供相关科学依据。方法 2011年9月至2012年3月,针对徐州市区20岁及以上常住人口,采用多阶段分层整群随机抽样的方法,共调查2446人,其中男性1197例,女性1249例,对该人群进行问卷调查,并进行空腹血糖测定、口服葡萄糖耐量试验(OGTT),测量身高、体重、腰围、臀围、血压,计算体质指数(BMI)、腰臀比,测定总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)和血尿酸(UA)水平。采用1999年世界卫生组织(WHO)制定的DM及IGR诊断标准,计算患病率。对DM相关危险因素进行多因素非条件logistic回归分析。结果徐州市区居民DM患病率为14.88%,标化率为12.33%,其中男性为12.15%,女性为12.52%,差异无统计学意义(χ2=0.467,P>0.05)。IGR患病率为19.91%,标化率为17.59%,其中男性为17.55%,女性为17.68%,差异无统计学意义(χ2=0.139,P>0.05)。多因素非条件logistic回归分析结果发现,中心性肥胖(OR=2.036,95%CI:1.525～2.718)、超重和肥胖(OR=1.870,95%CI:1.418～2.465)、年龄(OR=1.718,95%CI:1.267～2.329)、运动量少(OR=1.565,95%CI:1.072～1.395)、高血脂[高TG(OR=1.502,95%CI:1.052～2.144)、高TC(OR=1.289,95%CI:1.153～1.428)、高LDL-C(OR=1.560,95%CI:1.283～1.907)]、高血压(OR=1.474,95%CI:1.252～1.778)、DM家族史(OR=1.283,95%CI:1.153～1.428)、主食摄入量大(OR=1.010,95%CI:1.001～1.019)为DM的重要危险因素。结论徐州市DM及IGR人群患病率明显增高,中心性肥胖、超重和肥胖、年龄增长及血脂水平、血压增高可能是导致DM患病率升高的主要原因。Objective To investigate the morbidities of diabetes mellitus （DM） and impaired glucose regulation （IGR）, to analyze the related risk factors among urban residents in Xuzhou and to provide the scientific bases for preventing and treating the diabetes mellitus. Methods A total of 2 446 residents （including 1 197 males and 1 249 females） aged above 20 years were selected with multi-stage stratified and cluster sampling method and investigated by a questionnaire, physical examinations （height, weight, waist, hips, waist-hip ration, blood pressure and BMI） and laboratory tests （TC, TG, HDL-C, LDL-C and UA） from September of 2011 to March of 2012.According to the criteria of DM and IGR of WHO in 1999, the morbidities of DM and IGR were calculated. The multivariate unconditional logistic regression was used to analyze the related risk factors. Results The morbidity and standardized morbidity of DM were 14.88% and 12.33% （male： 12.15% and female： 12.52%） among urban residents in Xuzhou. The morbidity and standardized morbidity of IGR were 19.91% and 17.59% （male： 17.55% and female： 17.68%） among urban residents in Xuzhou. There were no significant differences between males and females. The multivariate unconditional logistic regression indicated that the risk factors of DM were the central obesity （OR=2.036, 95%C1=1.525~2.718）, overweight and obesity （0R=1.870, 95%C1=1.418-2.465 ）, age （OR = 1.718, 95% CI= 1.267 -2.329）, less exercise （ OR = 1.565, 95%CI= 1.072-1.395）, hyperlipidemia （high TG： 0R=1.502, 95%CI=1.052-2.144; high TC： 0R=1.289, 95%CI=1.153-1.428; high LDL-C： 0R=1.560, 95%CI=1.283- 1.907）, hypertension （OR= 1.474, 95%CI= 1.252-1.778 ）, DM family history （OR= 1.283, 95%C1= 1.153-1.428） and large amount of staple food intake （OR=I.010, 95%CI=1.001-1.019）. Conclusion The morbidities of DM and IGR among urban residents in Xuzhou significantly increase, the central obesity, overweigh and obesity, age, blood pressure and blood lipid may be t

关 键 词：糖尿病 糖调节受损 患病率 危险因素 

分 类 号：R587.1[医药卫生—内分泌]