经肾动脉栓塞术对常染色体显性多囊肾病终末期的对症治疗  

Renal arterial embolization for symptomatic management of end-stage autosomal dominant polycystic kidney disease

作　　者：孟小茜[1] 董伟华[1] 王智[1] 廖华强[1] 刘士远[1] 肖湘生[1] 

机构地区：[1]上海第二军医大学长征医院影像科,200003

出　　处：《介入放射学杂志》2013年第6期461-463,共3页Journal of Interventional Radiology

摘　　要：目的评价经肾动脉栓塞术在常染色体显性多囊肾病对症治疗中的安全性和疗效。方法2007年12月至2013年3月收治终末期多囊肾病患者7例,因内科保守治疗无效而行肾动脉栓塞术治疗。7例患者均表现为严重腹胀,5例伴肉眼血尿,1例伴顽固性高血压。结果术后随访10～36个月,7例患者临床症状均有不同程度缓解,同时腹围变小,营养状况改善。无严重并发症发生。结论经肾动脉栓塞术对终末期多囊肾的对症治疗是安全有效的。Objective To evaluate the efficacy and safety of transarterial embolization for symptomatic management of end-stage autosomal dominant polycystic kidney disease. Methods During the period from December 2007 to March 2013, seven patients with end-stage autosomal dominant polycystic kidney disease were admitted to the hospital. As the patients failed to respond to medical conservative measures transarterial embolization therapy using PVA particles, Gelfoam or coils was carried out in all of them. Clinically, the primary manifestation of the disease was severe abdominal distension in all patients. Gross hematuria was seen in 5 cases and refractory hypertension in one case. Results Unilateral renal arterial embolization was successfully performed in 6 patients, while bilateral renal arterial embolization was accomplished in one patient. All patients were followed up for 10 - 36 months. Different degrees of improvement in clinical symptoms were obtained in all the patients. The abdominal perimeter decreased, and the patient＇s nutritional status was improved. No severe complications occurred. Conclusion For the symptomatic management of end-stage dominant polycystic kidney disease, renal arterial embolization is safe and effective. （J Intervent Radiol, 2013, 22： 461-463）

关 键 词：常染色体显性多囊肾病 动脉栓塞 对症治疗 

分 类 号：R692.1[医药卫生—泌尿科学]