急性冠状动脉综合征及合并2型糖尿病患者非罪犯病变的血管内超声-虚拟组织学特点的研究  

Intravascular ultrasound and virtual histology study on nonculprit lesion in acute coronary syndrome patients with type 2 diabetes mellitus

作　　者：郑婕舒[1] 张元春[1] 贺迅[1] 戴磊[1] 罗常有[1] 刘祖恒[1] 尹庆[1] 王善花[1] 苏伟平[1] 

机构地区：[1]中山大学附属东华医院心内科,东莞523110

出　　处：《中国糖尿病杂志》2013年第6期524-526,共3页Chinese Journal of Diabetes

基　　金：2012年广东省省级科技计划项目(2012B031800272)

摘　　要：目的急性冠状动脉综合征(ACS)及合并T2DM患者非罪犯病变的血管内超声-虚拟组织学(IVUS-VH)特点与罪犯病变进行比较,为临床处理非罪犯病变提供参考。方法选取ACS患者60例,其中合并T2DM 17例,入选者分别行3条血管IVUS-VH检查,测量病变的IVUS-VH指标,检出薄纤维帽粥样斑块(VH-TCFA),确定罪犯病变后分为罪犯病变组(A组)与非罪犯病变组(B组)进行比较。结果两组VH-TCFA检出率一致(66.7%vs 66.7%,P=1.000)。结论ACS患者(包括合并T2DM)非罪犯病变同样具有易损性。Objective To compare the characteristics of non-culprit lesion with culprit lesion in acute coronary syndrome （ACS） patients with T2DM to provide the references for the clinical management of non-culprit lesion. Methods The 3-vessel intravaseular ultrasound and virtual history （IVUS-VH） analysis was performed for 60 ACS patients, 17 of them with T2DM. The parameters of IVUS-VH were measured for all the lesions. The thin-cap fibroatheromas （VH-TCFA） were detected. After the culprit lesion was diagnosed first, the culprit and nonculprit lesion groups were compared to observe the characteristics between them. Results The detectable rate of IVUS-VH derived thin-cap fibroatheroma （VH-TCFA） was the same （66.7% vs 66. 7%, P=1. 000） in the nonculprit versus culprit lesion groups. Conclusion Noneulprit. lesion is vulnerable in ACS patients （some of them with T2DM）.

关 键 词：急性冠状动脉综合征 糖尿病 2型 血管内超声-虚拟组织学 非罪犯病变 

分 类 号：R541.4[医药卫生—心血管疾病]