广安门医院活动期类风湿关节炎中医处方规律分析  

Laws Analysis of Traditional Chinese Medicine Prescriptions for Active Rheumatoid Arthritis from Guang'anmen Hospital

作　　者：李德平[1] 翟华强[1] 曹炜[2] 刘鹏霄[2] 王清林[2] 员晶[3] 

机构地区：[1]北京中医药大学中药学院,北京100102 [2]中国中医科学院广安门医院,北京100053 [3]浙江中医药大学第三临床医学院,杭州313200

出　　处：《中国实验方剂学杂志》2013年第12期341-344,共4页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：中国博士后科学基金特别资助项目(201003222)

摘　　要：目的:分析中国中医科学院广安门医院治疗活动期类风湿关节炎(RA)中医处方药性特点和配伍规律。方法:收集、整理广安门医院2009年7月至2012年7月活动期RA住院患者的中医处方,在构建数据库的基础上,应用SPSS 16.0软件进行频数分析,采用关联规则计算相关度。结果:收集的99例患者共314首处方中,出现频率>50%的有13味药,分别为薏苡仁、赤芍、苍术、当归、羌活、茯苓、川牛膝、金银花、黄柏、黄芪、青风藤、土茯苓、白术;四气以性寒居多,性温其次;五味以苦、甘、辛较多;归经以肝经最多,归胃、脾经其次;有毒性中药共占5.81%;相关度较高的为苍术、川牛膝、黄柏、薏苡仁,当归、川芎、赤芍,金银花、薏苡仁,茯苓、白术,丹皮、赤芍等药对。结论:广安门医院治疗活动期RA从湿、热、瘀论治,采用清热除湿活血法,注重肝的疏泄调养,同时不忘顾护脾胃。Objective： To analyze medicinal characteristics and compatibility laws of traditional Chinese medicine（TCM） for active rheumatoid arthritis（RA） from Guang’anmen hospital.Method： Collected and collated TCM prescriptions of hospitalized patients in Guang’anmen hospital from July 2009 to July 2012 on active RA.In the foundation of database,we analyzed frequency with SPSS 16.0 software and calculated correlation degree with association rules.Result： We had collected 314 prescriptions of 99 cases of patients.There were thirteen herbs,frequency of which in prescriptions was more than 50%,such as Angelica sinensis,Coix lacrymajobi,Paeonia lactiflora,ect.The cold herbs was the most,then was the the warn herbs;The bitter,sweet and spicy herbs respectively;Herbs belonging to liver was the most,then was the herbs belonging to stomach and spleen;toxic Chinese medicines accounted for 5.81% in all.High correlation of the herbs was Atractylodis Rhizoma/Cyathulae Radix/Phellodendri Chinensis Cortex/Coicis Semen,Angelicae Sinensis Radix/Chuanxiong Rhizoma/Paeoniae Rodix Rubra and other couplet medicines.Conclusion： Guang’anmen hospital treated active RA with heat cleaning/dehumidification/activating blood method based on wet,heat and stasis.They paid much attention to the function of liver,also did not forget to regulate function of the spleen and the stomach.

关 键 词：活动期类风湿关节炎 中药药性 处方规律 

分 类 号：R283.6[医药卫生—中药学]