聘用专职督导员管理TB/HIV双重感染患者的效果研究  

Investigation of the effects that employing full-time supervisor to manage the TB/HIV co-infection patients

作　　者：肖文联[1] 胡天桥[1] 胡洋[1] 

机构地区：[1]柳州市疾病预防控制中心,广西柳州545007

出　　处：《现代预防医学》2013年第12期2262-2264,共3页Modern Preventive Medicine

基　　金：广西壮族自治区卫生厅自筹经费科研课题(Z2008392)

摘　　要：目的探讨聘用专职督导员管理TB/HIV双重感染患者的干预效果。方法按入院先后顺序编号采用随机数字表的方法随机化分组,干预组采用专职督导员对TB/HIV双重感染病人进行管理和追踪,对照组采用门诊随诊自行管理。结果干预组患者规范完成疗程率88/106人(83.0%)明显高于对照组70/106人(66.0%)(χ2=8.051,P﹤0.05);干预组中途死亡、中断或间断服药人数分别为14、2、2人,远低于对照组的22、4、10人(χ2=9.828,P﹤0.01),干预组6月的CD4细胞水平(145.7±12.5)个/μl明显高于对照组(118.1±15.1)个/μl(t=14.496,P﹤0.01)。结论此干预措施确实能改善患者规范服药治疗的依从性,提高治疗效果。OBJECTIVE To improve the treatment compliance of patients infected with tuberculosis （TB） as well as AIDS by employing full-time supervisor to manage them. METHODS According to the order of admission, patients were divided into two groups by using random number table. The intervention group co-infected with TB/HIV was managed and tracked by full-time supervisor while the control group was managed by themselves after discharge. RESULTS 83.0% of patients in con- trol group had successfully completed the course of treatment whereas only 32.42% patients in the observation group completed that. The number of patients interrupted treatment or intermittent treatment or died during the treatment in control group were 14, 2, 2 respectively whereas the number of patients in the observation group were 22, 4, 10. The CD4 cell level had been obviously improved in the intervention group. CONCLUSIONS With the interventions, the treatment compliance of patients co-infected with TB/HIV is improved.

关 键 词：TB HIV双重感染患者 治疗依从性 干预 

分 类 号：R52[医药卫生—内科学]