2000-2011年邢台市儿童HIV感染状况调查  

Survey on the HIV Infection Status Among Children in Xingtai City from 2000 to 2011

作　　者：徐智贤[1] 李晓梅 李春梅 王志苏[1] 刘福宝[1] 

机构地区：[1]河北省邢台市疾病预防控制中心,河北邢台054000 [2]河北省沙河市疾病预防控制中心

出　　处：《实用预防医学》2013年第6期698-700,共3页Practical Preventive Medicine

摘　　要：目的掌握邢台市儿童HIV感染状况。方法对2000-2011年邢台市检出的109例具有母婴传播危险因素HIV阳性育龄妇女及其所生的155例子女进行流行病学调查,并采集血样进行HIV抗体检测。结果 155例子女中,检出儿童HIV感染者48例。母婴传播感染率为30.1%（48/155）。155例中有母乳喂养史119例,检出HIV感染43例,母乳喂养感染率为36.1%（43/119）。存在单纯母乳喂养因素和宫内、分娩、母乳3个因素的感染率分别为36.8%（32/87）、34.4%（11/32）;人工喂养感染率为13.9%（5/36）。存在母乳喂养因素的母婴传播组HIV感染率36.1%（43/119）显著高于人工喂养的母婴传播组13.9%（5/36）。儿童HIV感染者年龄以6~12岁为主,占83.3%;感染者主要分布在沙河市40例,占83.3%;母乳喂养为主要感染途径,占感染者总数的89.6%（43/48）;母乳喂养时间较长,平均2周岁;导致艾滋病儿童死亡直接原因分别为多器官功能衰竭、呼吸衰竭、脑水肿。结论母乳喂养是邢台市儿童感染HIV的主要途径。Objective To investigate children＇s HIV infection status in Xingtai City.Methods Totally,109 HIV-positive women of reproductive age who had the risk factors for mother-to-child transmission were detected in Xingtai City during the period of 2000-2011.All women and their children（n=155） were surveyed epidemiologically,and their blood samples were drawn to perform HIV antibody test.Results Among the 155 children,48 were detected with HIV positive.Mother-to-child HIV transmission rate was 30.1%（48/155）.119 children had ever been breastfed,43 were detected with HIV positive and the subsequent infection rate through breastfeeding was 36.1%（43/119）.The infection rates of exclusive breastfeeding and the three-risk-factors（simultaneously including intrauterine,childbirth,and breastfeeding transmission） were 36.8%（32/87） and 34.4%（11/32）,respectively.The infection rate of artificial feeding was 13.9%（5/36）.The HIV infection rate in mother-to-child transmission group with the risk factor of breastfeeding（36.1%,43/119） was significantly higher than that in mother-to-child transmission group with artificial feeding（13.9%,5/36）.Most of HIV-positive children ranged in age from 6 to 12 years,accounting for 83.3%.The infected children were mainly distributed in Shahe City（n=40）,accounting for 83.3%.The main route of HIV infection was breastfeeding,accounting for 89.6%（43/48）.The duration of breastfeeding was longer,with an average of 2 years.The direct causes of the death of HIV-positive children were multiple organ failure,respiratory failure and hydrocephalus.Conclusion Breastfeeding is the main way of HIV infection among children in Xingtai City.

关 键 词：儿童 HIV感染 母婴传播 母乳喂养 

分 类 号：R512.91[医药卫生—内科学]