子痫患者β_2-微球蛋白和胱抑素-C联合检测的临床意义  

The clinical significance of the detection ofβ_2-microglobin and cystatin C to eclampsia

作　　者：信朝霞[1] 

机构地区：[1]唐山市工人医院,河北唐山063000

出　　处：《临床医药实践》2013年第6期443-444,466,共3页Proceeding of Clinical Medicine

摘　　要：目的:评估血清β2-微球蛋白和胱抑素-C的联合检测在子痫前期及子痫患者中的诊断价值。方法:对近期收治的子痫前期及子痫患者102例(实验组)及正常孕晚期孕妇50例(对照组)进行β2-微球蛋白和胱抑素-C的检测,并进行对比研究。结果:与对照组相比,实验组患者β2-微球蛋白和胱抑素-C水平均升高,胱抑素-C水平升高尤为显著。β2-微球蛋白对子痫的诊断敏感性为74.6%,特异性为78.8%;胱抑素-C对子痫的诊断敏感性为85.4%,特异性为90.2%;而二者联合检测对子痫的诊断敏感性为91.3%,特异性为92.6%。结论:联合检测β2-微球蛋白和胱抑素-C可以及时对子痫患者进行早期诊断,提高诊疗效果。Objective：To investigate the detection ofβ2-microglobin and cystatin C in patients suffering from preeclampsia and eclampsia.Methods：Theβ2-microglobin and cystatin C of 102patients suffening from preeclampsia and eclampsia（test group）and 50healthy pregnant women（control group）were detected and compared.Results：The level ofβ2-microglobin and cystatin C in test group is higher than the control group,especially cystatin C.The senstivity of diagnosis ofβ2-microglobin to eclampsia is 74.6%,the specificity is 78.8%.And the senstivity of diagnosis of cystatin C to eclampsia is 85.4%,the specificity is 90.2%.The senstivity of combined examination is 91.3%,the specificity is 92.6%.Conclusion：β2-microglobin and cystatin C have a high specificity and sensitivity in the diagnosis of Eclampsia,can improve the diagnosis and treatment effect.

关 键 词：Β2-微球蛋白 胱抑素-C 子痫前期 子痫 

分 类 号：R714.245[医药卫生—妇产科学]