RP-HPLC法测定葛根芩连胶囊中盐酸小檗碱的含量  

Determination of Berberine Hydrochloride in Ge Gen Qin Lian Capsules By RP-HPLC

作　　者：孙冰[1] 詹祥静[1] 邓雨 李君 

机构地区：[1]华西医科大学制药厂,成都610041

出　　处：《成都大学学报（自然科学版）》2000年第1期7-10,共4页Journal of Chengdu University（Natural Science Edition）

摘　　要：用RP HPLC法测定葛根芩连胶囊中盐酸小檗碱的含量。采用ShimadzuVP ODS柱 ,乙腈 0 0 6mol/LKH2 PO4 SDS ( 2 50∶30 0∶3 3g)为流动相 ,检测波长 347nm。方法准确可靠 ,快捷方便 ,回收率为99 6 0 % ,RSD为 1 0 6 %。An RP HPLC method is developde to determine Berbering hydrochloride in Gegen Qinlian Capsules The RP HPLC conditions were CH 3CN 0 06 mol/L KH 2PO 4 SDS(250∶300∶3 3g) as mobile phase, shimadzu VP ODS(4 6mm×150mm, 5μm) colume, detection at 347nm The average recovery is 99 60%, RSD was 1 06% This method was accurate, simple and rapid

关 键 词：反相高效液相色谱 葛根芩连胶囊 盐酸小檗碱 

分 类 号：R284[医药卫生—中药学]