毛大丁草叶醇提物对大鼠离体子宫的作用  

In Vitro Study of the Effect of Gerbera piloselloides Ethanol Extract on the Uterus of Rat

作　　者：柳斌[1] 郭美仙[1] 刘勇[1] 陆翠芬[1] 刘光明[1] 陈光勇[1] 

机构地区：[1]大理学院药学与化学学院,云南大理671000

出　　处：《大理学院学报（综合版）》2013年第6期90-92,共3页Journal of Dali University

基　　金：大理州科技局科研基金资助项目(2060402);大理学院大学生科研基金资助项目(DXSKYY201123)

摘　　要：目的:研究毛大丁草叶醇提物对大鼠离体子宫的作用。方法:取成熟雌性未孕大鼠,用击打法处死,取子宫角制备大鼠离体子宫段,采用BL-420E+生物机能系统记录子宫张力信号,观察毛大丁草叶醇提物对大鼠离体子宫自发收缩和催产素诱发收缩的影响。结果:毛大丁草叶醇提物可以使大鼠离体子宫收缩频率减慢、强度减小和活动力减弱。结论:毛大丁草叶醇提物对大鼠离体子宫自发收缩和催产素诱发收缩均具有明显的抑制作用。Objective： To investigate the effect of ethanol extract from leaves of Gerbera piloselloides on the uterus of rat in vitro. Methods： Ten mature female but not pregnant SD rats were executed by strike, and uterine horus were used for the rat uterus segment in vitro. BL-420E ＋ Biological Functional System was used to record uterine tension, the effect of Gerbera piloselloides Ethanol Extract on spontaneous contraction and oxytocin-induced contraction of uterus were recorded. Results： The extract could slow down the uterine contraction frequency and decrease the contraction intensity, and weaken the uterine motility as well. Conclusion： The ethanol extract of Gerbera piloseUoides has significant inhibitive effect on the spontaneous contraction and oxytocininduced contraction of rat uterus in vitro.

关 键 词：毛大丁草叶 醇提物 大鼠 离体子宫 

分 类 号：R285.5[医药卫生—中药学]