宫颈上皮内瘤变锥切术后复发现状和影响因素调查研究  

Investigation on the Status and Influence Factors of Recurrence After Cervical Intraepithelial Neoplasia Conization

作　　者：陈雪梅[1] 

机构地区：[1]广东省肇庆市怀集县人民医院,广东肇庆526400

出　　处：《临床医学工程》2013年第6期761-762,共2页Clinical Medicine & Engineering

摘　　要：目的探讨宫颈上皮内瘤变锥切术后复发的现状和影响因素。方法采用自编问卷调查2008年1月至2012年1月在我院妇科收治的98例宫颈上皮内瘤变患者为研究对象,进行为期1年的随访,根据患者复发与否将本研究入组患者分为对照组和观察组,采用描述性统计和二分类Logistic回归分析宫颈上皮内瘤变锥切术后复发现状和影响因素。结果宫颈上皮内瘤变锥切术后复发率较高,多因素Logistic回归分析显示CIN病变的级别高、术后切缘阳性、颈管腺体累及、患者绝经和人乳头状瘤病毒(HPV)持续感染是宫颈上皮内瘤变锥切术后患者复发的危险因素。结论宫颈上皮内瘤变复发率较高,复发受多方面因素影响,我们应该采取针对性的预防干预措施来降低患者的复发率,提高患者的生活质量。Objective To investigate the status and influence factors of recurrence of cervical intraepithelial neoplasia （CIN） atter conization. Methods 98 patients with CIN in our hospital from January 2008 to January 2012 were selected and investigated by the self-designed questionnaire; all cases were followed up for 1 year, and divided into the observation group and the control group depending on recurrence or not. The status and influence factors of postoperative recurrence were analyzed through the descriptive statistics and classified Logistic regression analysis. Results The recurrence rate after CIN conization was high. Multivariate Logistic regression analysis showed that CIN lesions of the high level, postoperative positive margin, involved cndocervical glands, menopause and human papilloma virus （HPV） infection were the risk factors for the recurrent Of C1N after conization. Conclusions CIN has high recurrence, and it is affected by various factors, which means we should take targeted prevention interventions to reduce the recurrence and improve patients＇ life quality.

关 键 词：宫颈上皮内瘤变 复发 影响因素 预防干预 

分 类 号：R195.4[医药卫生—卫生统计学]