氟比洛芬酯复合盐酸右美托咪定用于高血压患者甲状腺手术中的临床观察  

Clinical observation of Flurbiprofen axetil combined with dexmedetomidine hydrochloride for patients with hypertension in thyroid operation

作　　者：洪玉丽[1] 

机构地区：[1]黑龙江省大庆油田总医院,163001

出　　处：《齐齐哈尔医学院学报》2013年第11期1606-1607,共2页Journal of Qiqihar Medical University

摘　　要：目的本研究旨在观察氟比洛芬酯超前镇痛复合右美托嘧啶用于高血压患者甲状腺手术中血流动力学的改变及术后镇痛等方面的作用。方法 50例甲状腺手术的高血压患者随机分为两组,氟比洛芬酯+盐酸右美托咪定组(D组)和对照组(C组),观察入室时(T0)、切皮时(T1)、分离肿瘤时(T2)、手术结束缝皮时(T3)患者HR、MAP值、镇静与镇痛评分。结果 Ramsay镇静评分D组明显高于C组。D组患者各时间点HR、MAP值低于C组(P<0.05)。D组VAS评分明显低于C组,(P<0.01)。结论氟比洛芬酯复合右美托嘧啶后镇静镇痛良好,不良反应发生率较低,术后遗留不良记忆减少,术后镇痛良好,值得临床采用。Objective To observe the effect of preemptive analgesia of flurbiprofen axeti combined with dexmedetomidine hydrochloride for hypertensive patients in thyroid operation and postoperative analgesia or other aspects. Methods 50 cases of hypertensive patients in thyroid operation were randomly divided into 2 groups, flurbiprofen axeti combined with dexmedetomidine hydrochloride （D group） and control group （C group）. HR, MAP, Ramsay sedation score and VAS grade were monitored and recorded before operation （T0）, skin incision （T1）, Isolation of tumor（T2）, at the end of operation（T3 ）. Results Ramsay sedation score was significantly higher in group D than group C. HR, MAP value in group D at each time point were lower than group C （P 〈 0. 05）. VAS grade was obviously lower in group D than group C （ P 〈 0. 01 ）. Conclusions Flurbiprofen axeti combined with dexmedetomidine hydrochloride had better functions of sedation and analgesia, postoperative bad memory was reducing, postoperative analgesia was good, it was worthy of clinical use.

关 键 词：氟比洛芬酯 盐酸右美托咪定 高血压 甲状腺 

分 类 号：R971.3[医药卫生—药品]