乳腺癌预后危险因素分析  

The analysis of risk factors influencing prognosis of breast cancer

作　　者：陈熙昀[1] 谢芳[1] 

机构地区：[1]苏州大学医学部病理与病理生理系,江苏苏州215123

出　　处：《中国现代医药杂志》2013年第6期1-4,共4页Modern Medicine Journal of China

基　　金："莙政学者"研修计划及国家自然科学基金资助项目(编号:30672390)

摘　　要：目的探讨影响乳腺癌患者预后情况的高危因素,为制定有效的临床治疗方案奠定理论基础。方法对162例乳腺癌病例进行调查分析,采用Cox回归对所获得资料进行统计分析。结果不恰当的激素治疗可能是乳腺癌预后的危险因素,而雌激素受体和孕激素受体则具有保护作用。结论乳腺癌激素治疗的不恰当对乳腺癌的复发及转移有促进作用,在临床治疗方面尤其值得注意。Objective To analyze the risk factors which influence the prognosis of breast cancer, to investigate the treatment strategy of breast cancer in clinical. Methods 162 cases of breast cancer were analyzed by the single factor and the multi factors Cox regression analysis. Results Multi factors Cox regression analysis results indicated that the incorrect endocrine therapy may be risk factor which affected the patient’s prognosis of breast cancer. Hormone receptor status,extrogen receptor and extrogen receptor influenced the prognosis of breast cancer,and hormone receptor-positive group was better than that of the receptor-negative group. Conclusion The incorrect endocrine therapy may take part in the metastasis and recurrence of breast cancer.

关 键 词：乳腺癌 雌激素受体(ER) 孕激素受体(PR) 激素治疗 预后 

分 类 号：R737.9[医药卫生—肿瘤]