断指再植术后肝素抗凝治疗的风险评估  

Research of the Effect and Risk after Digital Replantation Treating with Heparin

作　　者：牟怡平[1] 张扬[1] 辛畅泰[1] 

机构地区：[1]沈阳医学院奉天医院手外科,辽宁沈阳110024

出　　处：《医学与哲学（B）》2013年第5期42-44,88,共4页Medicine & Philosophy(B)

摘　　要：为了研究断指再植术后用肝素抗凝对再植成活率的影响,将112例因完全离断行断指再植术的患者随机分成两组,对照组术后连续应用肝素10天,试验组仅术后应用48小时,对比两组再植术后血管危象的发生率、成活率及活化部分凝血活酶时间(APTT)。结果显示试验组血管危象发生率10.7%、成活率94.6%,对照组血管危象发生率8.9%(P>0.05)、成活率92.9%(P>0.05)。术后第10天试验组和对照组的APTT之间有差异(P<0.05)。所以术后长时间的应用肝素并不能降低血管危象的发生率,也不能提高再植的成活率,相反却会导致APTT延长。To evaluate the success rates after digital replantation with using heparin, 112 patients were divided into two groups ran- domly. The experimental group was treated with heparin in the next l0 days after replantation,and the control group only in 48h. The survival rates and APTT were observed after replantation in two groups. The rates of blood vessels insufficiency was 10.7 % and the success was 94.6 % in the experimental group, well it was 8.9 % and 92.9% respective in the control group（P〈0.05）, which showed no significant difference between two groups. There was an obvious difference （P〈0.05） between two groups in the value of APTT. So there was not helpful for improving the rate of the blood vessels insufficiency and success with using the heparin even longer after the repIantation, hut would increase the APTT.

关 键 词：断指再植 肝素 抗凝 成活率 

分 类 号：R658.1[医药卫生—外科学]