甲基睾丸素加强米非司酮配伍米索前列醇终止12～14周妊娠的临床研究  

A Clinical study of the Role of Mifepristone and methyl - testoderone Combinging With Mispoprostol in Terminating 12 ～ 14 Weeks Pregnancy

作　　者：刘其芬[1] 冯丽光[1] 胡丽娜[1] 卢娜[1] 

机构地区：[1]重庆医科大学附属第二医院妇产科,400010

出　　处：《重庆医学》2000年第5期402-403,共2页Chongqing medicine

摘　　要：目的 探索甲基睾丸素（简称甲睾）加强米非司酮配伍米索前列醇（简称米索）终止１２～１４周妊娠的作用。方法实验组（加甲睾组）７０例，采用甲睾、米非司酮配伍米索终止妊娠；对照组５０例，采用米非司酮配伍米索终止妊娠。结果 实验组完全流产率５４．３％，总成功率７１．４％；对照组完全流产率４８．０％，总成功率６８．０％，两组无显著差异（Ｐ＞０．０５）。流产过程中出血量估计，实验组为 １０６．００±５９．９３ｍｌ，显著少于对照组 １３８．７５±６５．２３ｍｌ（Ｐ＜０．０５）。结论 米非司酮配伍米索是较好的药物终止１２～１４周妊娠的方法，加服甲睾可减少出血量。Objective: In this study, we observed the effect and method of adding methy - testosterone(MT) in mifepristone and misoprostol to terminate twelve to fourteen weeks pregnancy. Methods: Seventy women, in experiment group, were treated with mifepristone, misoprostol and MT for abortion and fifty women, in control group, were treated with only mifepristone and misoprostol. Results: In the experimental group, the complete abortion rate was 54. 3 percent, and the total successful rate was 74. 1 percent; In the control group, the complete abortion rate was 48. 0 percent, and the total successful rate was 68. 0 percent.There was no marked difference between the two groups(P >0. 05), but the blood loss in experi- ment group was 106.00± 59. 93ml, much less than 138. 75 ±65. 23ml in control group(P < 0. 05). Conclusion: It is a good way to administer mifepristone combining with misoprostol to terminate 12 to 14 weeks pregnancy. If MT is added, the amount of blood loss will be decreased.

关 键 词：甲基睾丸素 米非司酮 米索前列醇 药物流产 

分 类 号：R169.42[医药卫生—公共卫生与预防医学]