治疗男性性机能障碍药物的研究与开发  

Research and Development of Therapeutic Drugs for Erectile Dysfunction

作　　者：陈亮[1] 何凤慈[1] 江远明[2] 

机构地区：[1]第三军医大学野战外科研究所大坪医院药剂科,重庆400042 [2]华西医科大学药学院临床药学系,四川成都610041

出　　处：《药学进展》2000年第4期197-200,共4页Progress in Pharmaceutical Sciences

摘　　要：男性性机能障碍成为社会广泛关注的疾病 ,且其形成原因复杂。目前 ,治疗该疾病的给药方法主要有注射和口服两种 ,经注射途径给药的药物有 :前列地尔、前列腺素E1和E2 、罂粟碱、莫西赛利、睾酮及拟降钙素肽 ;经口服途径给药的药物有 :甲磺酸酚妥拉明、溴隐亭、阿朴吗啡、曲唑酮、精氨酸和西地那非等。本文介绍了上述两种给药途径的治疗男性性机能障碍药物的作用特点、临床应用及开发状况。Erectile dysfunction has become the disease as concerned so much, with complex causes. Therapeutic drugs for erectile dysfunction, which are administried both parenterally and orally, were introduced, such as alprostadil, dinoprostone, phentolamine, papaverine, moxisylyte, testosterone, calcitonin gene related peptide, phentolamine meylate, bromocriptine, apomorphine, trazodone, arginine, sildenafil, et al. Their characteristics of action, clinical use and development update were also described.

关 键 词：男性性机能障碍 阳萎 药物 研究 开发 前列地尔 

分 类 号：R698[医药卫生—泌尿科学]