正常人肝脏3.0T磁共振弹性成像  

Magnetic resonance elastography for liver stiffness in healthy volunteers at 3.0T MR scanner

作　　者：石喻[1] 郭启勇[1] 张兰[1] 卞胜昕[1] 于兵[1] 

机构地区：[1]中国医科大学附属盛京医院放射科,辽宁沈阳110004

出　　处：《中国医学影像技术》2013年第6期941-944,共4页Chinese Journal of Medical Imaging Technology

基　　金：国家自然科学基金面上项目(81071123;81271566)

摘　　要：目的探讨我国正常成人肝脏磁共振弹性值测量的参考范围,分析弹性值与性别、年龄及体质量指数(BMI)的关系。方法对64名健康志愿者按年龄、性别、BMI分组,应用3.0T磁共振弹性成像(MRE)测量肝弹性值,统计分析肝弹性值与年龄、BMI的相关性,评价不同年龄、BMI及性别的组间差异。结果我国正常成人肝弹性值范围为1.83～3.02kPa,平均(2.37±0.28)kPa。肝弹性值与年龄、BMI均无相关性(r=0.20、0.02,P均>0.05)。男性平均肝弹性值略高于女性(U=309.00,P=0.01),不同年龄组、BMI组间肝弹性值的差异无统计学意义(χ2=3.31、2.16,P>0.05)。结论定量研究我国正常成人肝弹性值可为MRE的临床应用提供依据和指导。Objective To establish reference values of normal liver stiffness measured by magnetic resonance elastography （MRE）, and to determine whether the mean stiffness values are influenced by gender, body mass index （BMI） or age in Chinese. Methods Liver stiffness measurements were performed in 64 healthy volunteers with MRE at a 3.0T MR scan net. The correlation between liver stiffness values and the age and BMI, the differences among age, BMI and gender groups were analyzed using statistical methods. Results The mean stiffness value of liver was （2.37 ± 0. 28）kPa ranging from 1.83-3.02 kPa for healthy subjects. There was no correlation between the liver stiffness and age or BMI （r=0.20, 0.02, both P〉0.05）. The mean liver stiffness value was higher for men than that for women （U=309.00, P=0. 01）. No significance was found among age or BMI group （X^2=3.31, 2.16, P〉0.05）. Conclusion Quantitative measurement of liver stiffness values in normal adult Chinese can be applied as references in future clinical studies.

关 键 词：肝脏 弹性成像技术 健康志愿者 

分 类 号：R445.2[医药卫生—影像医学与核医学] R3[医药卫生—诊断学]