经直肠实时组织弹性成像联合血清PSA对前列腺良恶性结节的鉴别诊断价值  

Transrectal Real-time Tissue Elastography Combined with Serum PSA in the Differential Diagnosis of Prostate Benign and Malignant Nodules

作　　者：韩来福[1] 林萍[1] 邹蕊[1] 孙卫兵 冯晓海 夏稻子[1] 

机构地区：[1]大连医科大学附属第二医院超声科,辽宁省大连市116027 [2]泌尿外科 [3]病理科

出　　处：《中国超声医学杂志》2013年第6期520-522,共3页Chinese Journal of Ultrasound in Medicine

摘　　要：目的探讨经直肠实时组织弹性成像(TRTE)联合血清前列腺特异性抗原(PSA)对前列腺良恶性结节的鉴别诊断价值。方法对89例前列腺结节患者,行TRTE及血清PSA联合诊断,与病理结果对照并进行统计学分析。结果前列腺良恶性结节实时组织弹性成像(RTE)应变指数(SI)之间比较,差异有统计学意义(P<0.05)。由ROC曲线可知,当SI切点值为7.50时,曲线下面积为0.896,诊断敏感性、特异性及准确性分别为83.87%、72.41%、76.41%;TRTE和PSA联合诊断时,其敏感性、特异性及准确性分别为93.55%、89.66%、91.0%。结论 TRTE联合血清PSA可提高前列腺癌(PCa)的诊断率,为前列腺良恶性结节的鉴别诊断提供有价值的信息。Objective To investigate the value of transrectal real time tissue elastography（TRTE） comhined with serum prostate specific antigen（PSA） in the differential diagnosis of prostate benign and malignant nodules. Methods 89 patients with prostate nodules underwent TRTE and serum PSA detection. The results were analysed statistically compared with pathology. Results The differences of RTE strain index（SI） between benign nodules and malignant nodnles showed statistical significance. According to the ROC curve, when the cut off point of SI was 7.50, the area under curve was 0. 896, and the diagnostic sensitivity, specificity, accuracy were 83.87%,72.41%,76.41%. The corn bination of TRTE and serum PSA improved the diagnostic sensitivity, specificity and the accuracy. The value were 93.55% ,89.66% and 91.00%. Conclusions Combination of TRTE and PSA can improve the diagnostic rate and or fer a valuable information in the differential diagnosis between prostate benign and malignant nodules.

关 键 词：腔内超声检查 实时组织弹性成像 前列腺肿瘤 前列腺增生症 前列腺特异性抗原 

分 类 号：R445.1[医药卫生—影像医学与核医学] R737.25[医药卫生—诊断学]