食蟹猴疟原虫和恶性疟原虫两种抗原检测不同疟区人群中间接荧光抗体的实用性  

PRACTICABILITY OF IFAT USING PLASMODIUM CYNOMOLGI AND PLASMODIUM FALCIPARUM ANTIGENS IN DIFFERENT MALARIOUS AREAS

作　　者：罗曼珍[1] 郑香[1] 尚乐园[2] 陈继峰[3] 祝卫东[1] 汤林华[1] 

机构地区：[1]中国预防医学科学院寄生虫病研究所 [2]河南省卫生防疫站,郑州450003 [3]海南省三亚市卫生防疫站,三亚522100

出　　处：《中国寄生虫学与寄生虫病杂志》2000年第1期49-51,共3页Chinese Journal of Parasitology and Parasitic Diseases

摘　　要：[目的 ]比较食蟹猴疟原虫 (P c.)和恶性疟原虫 (P f.)两种抗原在不同疟区人群疟疾抗体检测的实用性。 [方法 ]1997年 5～ 10月在海南省间日疟和恶性疟混合流行区及河南省单纯间日疟区用P c 和P f 两种抗原测试人群疟疾抗体。 [结果 ]在海南省间日疟和恶性疟混合流行区P c 和P f 两种抗原检测人群疟疾间接荧光抗体阳性率分别为 37 4%和 31 3% ,其阳性符合率为 83 9% ;河南省单纯间日疟流行区的P f和P c两种抗原阳性率分别为 2 3 0 %和 9 7% ,阳性GMRT分别为 42 9%和 2 9 3%。 [结论 ]间日疟和恶性疟混合流行区P f和P c两种抗原均可用于人群疟疾抗体的检测 ,而单纯间日疟地区则以P c 抗原为优。Objective] To compare the practicability of IFAT in different malarious areas using Plasmodium cynomolgi ( P c ) and Plasmodium falciparum ( P f )antigens. [Methods]This survey was carried out in Yaliang Township of Sanya City, Hainan Province, wherea mixed malaria is endemic, and in Tongbo County, Henan Province where only vivax malaria is endemic, and in Weihui City, Henan Province where vivax malaria has been under effective control since 1994～1998.[Results] In Yaliang Township, 310 blood samples were examined, the antibody positive rates with P c and P f were 37 4% and 31 3% ,respectively,the rate of coincidence being 83 9%. In Tongbo County, 300 blood samples were examined The antibody positive rates with P c and P f were 23 0% and 9 7%, respectively ( P <0 01). Another 245 blood samples from children were examined in Weihui City and the antibody positive rates were below 1% with two antigens, while the positive antibody rate was 3 3% with P f antigen.[Conclusion]Both P f and P c antigens could be used in malaria antibody surveillance in mixted endemic areas, while in vivax malaria endemic areas, P c antigen was recommended.

关 键 词：食蟹猴疟原虫 恶性疟原虫 IFAT 疟疾 抗原 

分 类 号：R531.304[医药卫生—内科学]