T细胞亚群测定鉴别结核性与癌性胸腔积液  

Differentiation of tubercular and carcinomatous pleural effusion by determination of T lymphocyte sub-populations

作　　者：于维霞[1] 王玉红[1] 郭悦鹏[1] 杜荣[1] 王涛[1] 

机构地区：[1]新乡医学院一附院,河南卫辉453100

出　　处：《新乡医学院学报》2000年第1期32-33,共2页Journal of Xinxiang Medical University

摘　　要：目的　探讨T细胞亚群对结核性和癌性胸腔积液的鉴别诊断意义。方法　采用碱性磷酸酶抗磷酸酶 (APAAP)法测定结核性和癌性胸腔积液患者外周血及胸腔积液中T淋巴细胞亚群。结果　结核性胸腔积液及外周血CD3、CD4T淋巴细胞亚群体均高于癌性胸腔积液组 (P <0 .0 5 ,P <0 .0 1) ,且癌性胸腔积液CD4/CD8比例倒置。Objective To study the significance of T lymphocyte sub-populations determination in differentiation of tubercular and carcinomatous pleural effusion. Methods T lymphocyte sub-populations in both pleural effusion and serum were determined by APAAP method in patients with tubercular or carcinomatous pleurisy. Results The CD 3 +, CD 4 + T lymphocyte populations of tubercular group were higher than that of carcinomatous group both in pleural effusion and blood, and the CD 4 +/CD 8 + ratio was converted in carcinomatous effusion. Conclusion Determination of T lymphocyte sub-populations is help for the differentiation of tubercular and carcinomatous pleural effusion.

关 键 词：胸腔积液 结核 肿瘤 T细胞亚群 鉴别诊断 测定 

分 类 号：R561.04[医药卫生—呼吸系统]