超声内镜引导下经支气管针吸活检与经支气管针吸活检对肺与纵隔病变诊断价值的对比研究  

Comparison study of endobronchial ultrasound-guided transbronchial needle aspiration and transbronchial needle aspiration for the diagnosis of hilar and mediastinal lesions

作　　者：吴齐[1] 曹长琦[1] 李士杰[1] 闫炎[1] 李香菊[2] 阎石[3] 吴楠[3] 张集昌[1] 

机构地区：[1]北京大学肿瘤医院暨北京市肿瘤防治研究所,恶性肿瘤发病机制及转化研究教育部重点实验室内镜中心,北京100142 [2]北京大学肿瘤医院暨北京市肿瘤防治研究所,恶性肿瘤发病机制及转化研究教育部重点实验室病理科,北京100142 [3]北京大学肿瘤医院暨北京市肿瘤防治研究所,恶性肿瘤发病机制及转化研究教育部重点实验室胸外二科,北京100142

出　　处：《北京大学学报（医学版）》2013年第3期464-468,共5页Journal of Peking University:Health Sciences

摘　　要：目的:比较超声内镜引导下经支气管针吸活检(endobronchial ultrasound-guided transbronchial needle aspi-ration,EBUS-TBNA)和经支气管针吸活检(transbronchial needle aspiration,TBNA)对肺与纵隔病变的诊断价值。方法:回顾性分析2010年1月至2011年5月接受EBUS-TBNA或TBNA检查的100例患者(EBUS-TBNA 50例,TBNA50例)的临床资料,总结穿刺结果和并发症发生率。结果:100例患者共穿刺121个部位,EBUS-TBNA组和TBNA组获得满意标本的比例分别为90.6%和78.9%。两组的诊断准确率分别为90.0%和72.0%,差异有统计学意义(P=0.022);严重并发症发生率均为0。结论:EBUS-TBNA与TBNA相比敏感性、特异性、诊断准确率更高,且不增加操作相关并发症,对肺与纵隔病变的诊断更有优势。Objective： To compare the values of endobronchial ultrasound-guided transbronchial needle aspiration （EBUS-TBNA） and TBNA for the diagnosis of hilar and mediastinal lesions. Methods：The clinical data of 100 patients who underwent EBUS-TBNA （n = 50） and TBNA （n = 50） between January 2010 and May 2011 were retrospectively reviewed, and the results and complications were recorded. Results：A total of 121 lesions in the 100 patients were evaluated, the sample yeilds of EBUS-TBNA and TBNA were 90.6% and 78.9% and the diagnostic accuracy rates in the two groups were 90.0% and 72.0% （P = 0. 022） , respectively. No major complications happened. The sensitivity, specificity and accuarcy of EBUS-TBNA were higher and the complication rate was not increased as compared with TBNA. Conclusion： EBUS-TBNA has a higher diagnostic yield for the evaluation of hilar and mediastinal lesions.

关 键 词：腔内超声检查 支气管镜检查 活组织检查 针吸 肺肿瘤 

分 类 号：R445[医药卫生—影像医学与核医学]