芪参复康胶囊治疗抑郁症的临床疗效观察  

The Efficiency of Qishenfukang Capsule in Depressive Disorder Patients.

作　　者：赵瑾[1,2] 贾婷[1] 吴兴曲[1] 杨来启[1] 李新田[1] 戴捷[1] 李亚萍[1] 

机构地区：[1]中国人民解放军第三医院全军精神疾病防治中心 [2]第四军医大学航空航天医学院

出　　处：《中国健康心理学杂志》2013年第6期830-831,共2页China Journal of Health Psychology

基　　金：军队中医药科研专项课题(10ZYX108)军队心理卫生科研课题(12XLZ303)

摘　　要：目的采用自身前后对照的方法观察芪参复康胶囊治疗抑郁症疗效。方法对30例抑郁症患者在治疗前及治疗6周后行汉密尔顿抑郁量表(HAMD)、抑郁自评量表(SDS)和脑电超慢涨落图检查,分析其治疗前后症状和脑内神经递质的变化。结果①抑郁症患者经芪参复康胶囊治疗6周后,HAMD总分和SDS总分均下降(t=15.95,11.81;P均<0.05),差异具体统计学意义;②抑郁症患者在治疗6周后脑内神经递质测量值较治疗前均有所变化,其中,5-羟色胺(5-HT)活动性降低,去甲肾上腺素(NE)、多巴胺(DA)活性增强(t=9.61,12.60,9.44;P<0.05),差异均具有统计学意义。结论纯中药制剂芪参复康胶囊治疗抑郁症疗效肯定。Objective To explore the efficiency of Qishenfukang capsule in depressive disorder patients with self-control study.Methods A total of 30 depressive disorder patients were detected with HAMD,SDS and encepha1of1uctuograph technology before therapy and after 6 week＇s therapy with Qishenfukang capsule.The scores of the two scales and changes of neurotransmitter were analyzed.Results ①The scores of the HAMD and SDS were significantly lower after 6 week＇s therapy with Qishenfukang capsule（t=15.95,11.81;P0.01）.The neurotransmitter showed some change after 6 week＇s therapy.The amount of 5-HT significantly increased（t=9.61,P0.01）.The amount of NE and DA significantly decreased than that before therapy（t=12.60,9.44,P0.01）.Conclusion Qishenfukang capsule is an effective drug to cure patients with depressive disorder and is worth to being applied.

关 键 词：芪参复康胶囊 神经递质 脑电超慢涨落技术分析 抑郁症 

分 类 号：R285.6[医药卫生—中药学]