布托啡诺静脉或硬膜外持续输注用于剖宫产术后镇痛的比较  

Comparison of analgesic effect of butorphanol intravenous or epidural continuous infusion in patients with cesarean section

作　　者：陈开文 

机构地区：[1]山东省单县妇幼保健院麻醉科,274300

出　　处：《中国实用医刊》2013年第13期46-47,共2页Chinese Journal of Practical Medicine

摘　　要：目的观察对比布托啡诺在剖宫产术后硬膜外或静脉镇痛的效果与不良反应。方法选择80例单胎足月妊娠孕妇，年龄19～38岁，ASAI～Ⅱ级。随机分为A、B两组，每组40例，A、B组均用布托啡诺8mg和氟哌利多1．25mg加生理盐水至100ml，以2ml／h的速度分别持续泵入，A组静脉泵入，B组经硬膜外腔泵入。记录两组产妇术后8、16、24、48h的VAS和Ramsay镇静评分及不良反应。结果两组患者术后不同时点VAS和Ram—say镇静评分及并发症情况比较差异均无统计学意义，且所有患者VAS评分基本都在3分以内，Ramsay镇静评分为2～3分。结论静脉或硬膜外持续泵注布托啡诺用于剖宫产患者镇痛镇静均满意，且无呼吸抑制作用，安全性均较高。Objective To observe the analgesic efficacy and side effects of butorphanol intrave- nous or epidural continuous infusion for postoperative analgesia in cesarean section. Methods Eighty cases of singleton pregnancy women who underwent cesarean section were selected, aged from 19 to 38 years, ASA Ⅰ - Ⅱ. They were randomly divided into two groups （ group A and group B） , with 40 cases in each group. Eight mg butorphanol and 1.25 mg droperidola were added in the analgesia pump and plus saline solution into 100 ml with respective speeds of 2 ml/h. Drugs were pumped into veins in Group A, and drugs were pumped into epidural in Group B. Ramsay, VAS scores and adverse reactions of the two groups at times 8, 16, 48 h after cesarean section were recorded. Results The VAS and Ramsay scores had no statistical differences between the two groups at the three different times and each patient＇ s VAS scores was less than 3, and Ramsay scores were between 2 - 3. Conclusions The analgesia and sedation effects is good when butor- phanol intravenous or epidural continuous infusion for postoperative analgesia in cesarean section, and has no respiratory depression, the security is high.

关 键 词：布托啡诺 镇痛 产科 

分 类 号：R614[医药卫生—麻醉学]