血清抗结核抗体IgG在肺结核临床诊断中的应用价值讨论  

Discussion on clinical application value of serum antibody IgG in diagnosing pulmonary tuberculosis

作　　者：刘晓燕 张正斌 孙静 王坚杰 田丹 

机构地区：[1]武汉市蔡甸区人民医院,武汉430100

出　　处：《公共卫生与预防医学》2013年第3期52-54,共3页Journal of Public Health and Preventive Medicine

摘　　要：目的探讨血清抗结核抗体IgG的临床应用价值及其影响因素。方法回顾性调查武汉市蔡甸区785例肺结核血清抗结核抗体IgG阳性率,并与健康人群进行对照,观察血清抗结核抗体IgG阳性率与痰检查结果、患者性别、病灶范围大小,有无空洞,是否排菌及排菌量多少的关系。结果血清抗结核抗体IgG检测结果显示肺结核患者阳性率为72.10%,健康人群阳性率为10.12%,肺结核患者抗结核抗体阳性率明显高于健康人群,其差异有统计学意义(&2=639.810;P<0.01)。抗结核抗体阳性率与病灶范围大小、空洞有无有密切关系,与患者性别、排菌量无关。结论血清抗结核抗体IgG检测在肺结核诊断尤其是涂阴肺结核诊断中具有一定的临床应用价值。Objective To explore the value of clinical application and the influencing factors of tuberculosis IgG antibodies in the serum of patients with lung tuberculosis.Methods Retrospective analysis method was applied to study serum IgG antibody positive rate of tuberculosis of 785 tuberculosis cases in Caidian district,to observe the relationships between serum IgG antibody positive rate of tuberculosis with sputum smear positive / negative,sex,scope of disease,whether cavity existed and amount of bacterium.Results The positive rate of serum IgG antibody in patients with lung tuberculosis was 72.10%,while it was 10.12% in healthy people,The differences were statistically significant（χ2 = 639.810;P〈0.01）.It was related to the scope of disease and whether cavity existed.However,there was no significant difference with sex and amount of bacterium.Conclusions Serum IgG antibody detection has certain value in clinical diagnosis of tuberculosis,especially for the sputum smear negative patients.

关 键 词：肺结核 IGG 诊断 

分 类 号：R521[医药卫生—内科学]