中西医治疗帕金森病抑郁症的临床研究  

Clinical Research of the Improvement of Parkinson Depression by Traditional Chinese Medicine

作　　者：刘璇[1] 薛红[1] 刘红敏[1] 

机构地区：[1]深圳市中医院,广东深圳518000

出　　处：《中医学报》2013年第7期1060-1061,共2页Acta Chinese Medicine

基　　金：深圳市科技计划项目(编号:201003175)

摘　　要：目的:探讨中西医治疗帕金森病伴抑郁症的临床疗效。方法:将60例帕金森病伴抑郁症患者按随机数字表法分为治疗组和对照组,每组各30例。对照组应用美多巴片0.125～0.250 g,每天3次,帕罗西汀20 mg,每日1次。治疗组在对照组的基础上合用中药辨证治疗,于治疗前及治疗8周后采用帕金森病统一评分量表(UPDRS)评定病情严重程度,汉密尔顿抑郁量表(HAMD)17项评定抑郁严重程度。结果:治疗组在治疗8周后UPDRS及HAMD评分明显减少,抗抑郁疗效有效率明显高于常规药物治疗组。结论:中西医治疗帕金森病抑郁症患者,能有效改善运动障碍和抑郁症状。Objective：To explore the clinical curative effect of traditional Chinese medicine treatment for Parkinson depression.Methods：60 patients with Parkinson disease were divided into TCM treatment group and control group according to random number table method.The control group was given Madopar piece 0.125-0.250 g,3 times a day,Paroxetine 20 mg,once daily.The treatment group was given Chinese medicine dialectical treatment based on the control group.Use unified Parkinson disease rating scale（UPDRS） to assess severity degree and Hamilton depressive scale（HAMD） to assess depression severity before and after 8 weeks treatment.Results：The UPDRS and HAMD scores in Chinese medicine treatment group were decreased significantly after 8 weeks treatment.The total effective rate of antidepressant effect in TCM treatment group was obviously higher than that in routine drug treatment group.Conclusion：Chinese medicine treatment in treating PD patients with depression can effectively improve dyskinesia as well as depressive symptoms.

关 键 词：帕金森病 抑郁症 美多巴片 帕罗西汀 

分 类 号：R277.7[医药卫生—中医学]