利用回交B_1和B_2及F_2群体鉴定数量性状两对主基因+多基因混合遗传模型  

Identification of Two Major Genes Plus Polygenes Mixed Inheritance Model of Quantitative Traits in B_1 and B_2, and F_2

作　　者：章元明[1] 盖钧镒[1] 王建康[2] 

机构地区：[1]南京农业大学大豆研究所农业部国家大豆改良中心,江苏南京210095 [2]河南省农科院实验中心,河南郑州450002

出　　处：《生物数学学报》2000年第3期358-366,共9页Journal of Biomathematics

基　　金：国家自然科学基金;国家973项目;重庆市科委应用基础研究项目

摘　　要：ＱＴＬ作图和主基因＋多基因混合遗传分析表明：拓展两对主基因＋多基因混合遗传模型十分必要．本文利用混合分布理论、 ＡＩＣ准则在回交 Ｂ１和 Ｂ２群体或 Ｆ２群体中鉴定两对主基因的存在，当主基因存在时估计其遗传参数；同时还改进了利用亲本、 Ｆ１和回交Ｂ１和 Ｂ２群体，或亲本、 Ｆ１和 Ｆ２群体鉴定多基因存在的方法．分布参数的估计采用 ＩＥＣＭ算法．以水稻株高性状为例说明该方法的应用．Both QTL mapping and the segregation analysis indicated that major gene plus polygene mixed model needs to be extended from one major gene to two or more major genes. Fortunately, the iterated ECM (IECM) algorithm makes it possible. In the present paper, Akaike's Information Criterion are employed to identify the exlstence of major genes affecting quantitative traits. Meanwhile, IECM algorithm is used to obtain the maximum likelihood estimates of parameters of component distributions, as well as the first order or second order genetic parameters. From P_1, P_2, F_1, B_1 and B_2 or P_1, P_2, F_1 and F_2, the likelihood ratio test is used to test the exlstence of polygenes. An example of the inheritance of rice plant height is provided.

关 键 词：数量性状 主基因+多基因混合遗传 IECM算法 

分 类 号：Q348[生物学—遗传学] Q-332